Andere Kunden interessierten sich auch für
![Design, synthesis and anti-HIV activity of curcumin analogues]( "Design, synthesis and anti-HIV activity of curcumin analogues")
Design, synthesis and anti-HIV activity of curcumin analogues26,99 €![Role of curcumin and its analogues in various diseases]( "Role of curcumin and its analogues in various diseases")
Role of curcumin and its analogues in various diseases26,99 €![Development of some novel Antimalarial agents]( "Development of some novel Antimalarial agents")
Development of some novel Antimalarial agents32,99 €![Pyridine Analogues As An Anticancer Agents]( "Pyridine Analogues As An Anticancer Agents")
Pyridine Analogues As An Anticancer Agents23,99 €![Synthesis of New Tamoxifen Analogues as Potential Anticancer Agents]( "Synthesis of New Tamoxifen Analogues as Potential Anticancer Agents")
Synthesis of New Tamoxifen Analogues as Potential Anticancer Agents36,99 €![Molecular properties prediction and synthesis of oxadiazole analogues]( "Molecular properties prediction and synthesis of oxadiazole analogues")
Molecular properties prediction and synthesis of oxadiazole analogues26,99 €![Pyridine Derivatives as Anti-malarial Agent]( "Pyridine Derivatives as Anti-malarial Agent")
Pyridine Derivatives as Anti-malarial Agent26,99 €
A series of dibenzylidencyclohexanone were synthesized by clasein-schmidt condensation reaction and twelve of them were evaluated in vitro for blood stage antiplasmodial properties in Plasmodium falciparum culture using SYBR- green-I uorescence assay. The structures of newly synthesized compounds were ascertained on the basis of their analytical and spectral profiles. The compound (2E,6E)-2,6-bis(3-nitrobenylidene) cyclohexanones (11) was found to be most active with IC50 of 66 g/ml against chloroquine sensitive (3d7)strain.Our results revealed that some of these exhibited promising antiplasmodial activities which can be further explored as potential leads for the development of cheaper, safe, effective and potent drugs against chloroquine-resistant malarial parasites.