Reproductive Toxicology (eBook, PDF)

Redaktion: Kapp, Robert W.; Tyl, Rochelle W.

• Format: PDF

Produktbeschreibung

An examination of the popular and expanding field of reproductive toxicology, this expanded third edition presents cutting-edge scientific developments in this constantly evolving discipline. Topics include epigenetic mechanisms and omics; the role of genomics, proteomics, and metabolomics in human reproduction; and new guidelines with respect to research applications in the field. The contributors are experienced regulatory agency and clinical research organization representatives who currently utilize the new techniques discussed in the text and continue to revolutionize reproductive toxicology research.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 512
• Erscheinungstermin: 19. April 2016
• Englisch
• ISBN-13: 9781420073447
• Artikelnr.: 42765875

Autorenporträt

Robert W. Kapp, Rochelle W. Tyl

Inhaltsangabe

Section I: Normal Reproduction and Development. 1. Biology and Physiology
of Fertilization. 2. Normal Development of the Male Reproduction System. 3.
Normal Development of the Female Reproduction System. 4. Development of the
Mammalian Nervous System. Section II: Regulatory Evaluation of
Reproduction. 5. EPA and OECD Perspectives on Reproductive and
Developmental Toxicity Testing. 6. FDA and ICH Perspectives on Reproductive
and Developmental Toxicity Testing. 7. Reproductive Study Evolution and IND
Submissions. Section III: Developmental Toxicity of Systemic Organ Systems.
8. Developmental Immunotoxicity. 9. Developmental Neurotoxicity. 10.
Developmental Toxicology of the Respiratory System. 11. Developmental
Toxicology of the Renal System. 12. Developmental Toxicology of the Liver.
13. Cardiovascular Development and Malformation. Section IV: Toxicity of
the Reproductive Process. 14. Male Reproductive Toxicity. 15. Female
Reproductive Toxicity. 16. Toxicity of Pregnant Female Reproductive System.
17. Epigenetic Reproductive Toxicants. 18. Endocrine Disruption Effects on
Reproductive Development and Adult Reproduction. 19. Metals and Metal
Compounds in Reproductive and Developmental Toxicology. 20. -omics in
Reproductive and Developmental Toxicology.