Natural Products Analysis (eBook, ePUB)
Instrumentation, Methods, and Applications
Redaktion: Havlicek, Vladimir; Spizek, Jaroslav
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Natural Products Analysis (eBook, ePUB)
Instrumentation, Methods, and Applications
Redaktion: Havlicek, Vladimir; Spizek, Jaroslav
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This book highlights analytical chemistry instrumentation and practices applied to the analysis of natural products and their complex mixtures, describing techniques for isolating and characterizing natural products. * Applies analytical techniques to natural products research - an area of critical importance to drug discovery * Offers a one-stop shop for most analytical methods: x-ray diffraction, NMR analysis, mass spectrometry, and chemical genetics * Includes coverage of natural products basics and highlights antibacterial research, particularly important as efforts to combat drug…mehr
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- Produktdetails
- Verlag: John Wiley & Sons
- Seitenzahl: 624
- Erscheinungstermin: 17. September 2014
- Englisch
- ISBN-13: 9781118876022
- Artikelnr.: 41530150
- Verlag: John Wiley & Sons
- Seitenzahl: 624
- Erscheinungstermin: 17. September 2014
- Englisch
- ISBN-13: 9781118876022
- Artikelnr.: 41530150
Methods, and Applications 1 Vladimír Havlíèek and Jaroslav Spí?ek 2. The
Need for New Antifungal and Antimalarial Compounds 9 Jaroslav Spí?ek and
Arnold L. Demain 3. Emerging Instrumental Methods for Antimicrobial
Resistance and Virulence Testing 25 Plamen A. Demirev 4. Plant and Marine
Sources: Biological Activity of Natural Products and Therapeutic Use 43
Amedeo Amedei and Elena Niccolai 5. Emerging Trends for Stimulating the
Discovery of Natural Products 115 Navid Adnani, Gregory A. Ellis, Thomas P.
Wyche, Tim S. Bugni, Jason C. Kwan, and Eric W. Schmidt 6. Advances and
Challenges in Optical Molecular Spectroscopy Including Surface Plasmon
Resonance-Based Methods for Bioanalysis 163 Pavel Matìjka, Blanka Vlèková,
Lucie Bednárová, and Petr Malon 7. Advanced Techniques for NMR Analysis of
Complex Biological Mixtures--From Simple NMR to Hyphenated Techniques 239
Helena Pelantová, Simona Bártová, and Marek Kuzma 8. Advances in X-Ray
Diffraction: Implications to the Pharmaceutical Industry 285 Alexandr
Jegorov and Michal Huaák 9. Laser Ablation Inductively Coupled Plasma Mass
Spectrometry as a Tool in Biological Sciences 313 Michaela Vaainová
Galiová, Jan Havlia, and Viktor Kanick? 10. Imaging Mass Spectrometry,
Metabolism, and New Views of the Microbial World 349 B. Christopher Hoefler
and Paul D. Straight 11. Structural Separations for Natural Product
Characterization by Ion Mobility-Mass Spectrometry: Fundamental Theory to
Emerging Applications 397 Sarah M. Stow, Nichole M. Lareau, Kelly M. Hines,
C. Ruth McNees, Cody R. Goodwin, Brian O. Bachmann, and John A. McLean 12.
High-Resolution Tandem Mass Spectrometry for Nonribosomal Peptide and
Polyketide Analysis 433 Rebecca H. Wills, Manuela Tosin, and Peter B.
O'Connor 13. Natural Product Drug Discovery and Analysis Using Mass
Spectrometry and Affinity-Based Technologies 475 Evelyn H. Wang and Kevin
A. Schug 14. Glycosylated Ribosomally Synthesized Peptide Toxins:
Discovery, Characterization, and Applications 507 Gillian E. Norris and
Mark L. Patchett 15. Using Ultrahigh-Resolution Mass Spectrometry to
Unravel the Chemical Space of Complex Natural Product Mixtures 545
Constanze Müller, Mourad Harir, Norbert Hertkorn, Basem Kanawati, Dimitrios
Tziotis, and Philippe Schmitt-Kopplin 16. Functional Amyloid Fibrils:
Lessons from Microbes 571 Sally L. Gras and Dennis Claessen Index 601
Methods, and Applications 1 Vladimír Havlíèek and Jaroslav Spí?ek 2. The
Need for New Antifungal and Antimalarial Compounds 9 Jaroslav Spí?ek and
Arnold L. Demain 3. Emerging Instrumental Methods for Antimicrobial
Resistance and Virulence Testing 25 Plamen A. Demirev 4. Plant and Marine
Sources: Biological Activity of Natural Products and Therapeutic Use 43
Amedeo Amedei and Elena Niccolai 5. Emerging Trends for Stimulating the
Discovery of Natural Products 115 Navid Adnani, Gregory A. Ellis, Thomas P.
Wyche, Tim S. Bugni, Jason C. Kwan, and Eric W. Schmidt 6. Advances and
Challenges in Optical Molecular Spectroscopy Including Surface Plasmon
Resonance-Based Methods for Bioanalysis 163 Pavel Matìjka, Blanka Vlèková,
Lucie Bednárová, and Petr Malon 7. Advanced Techniques for NMR Analysis of
Complex Biological Mixtures--From Simple NMR to Hyphenated Techniques 239
Helena Pelantová, Simona Bártová, and Marek Kuzma 8. Advances in X-Ray
Diffraction: Implications to the Pharmaceutical Industry 285 Alexandr
Jegorov and Michal Huaák 9. Laser Ablation Inductively Coupled Plasma Mass
Spectrometry as a Tool in Biological Sciences 313 Michaela Vaainová
Galiová, Jan Havlia, and Viktor Kanick? 10. Imaging Mass Spectrometry,
Metabolism, and New Views of the Microbial World 349 B. Christopher Hoefler
and Paul D. Straight 11. Structural Separations for Natural Product
Characterization by Ion Mobility-Mass Spectrometry: Fundamental Theory to
Emerging Applications 397 Sarah M. Stow, Nichole M. Lareau, Kelly M. Hines,
C. Ruth McNees, Cody R. Goodwin, Brian O. Bachmann, and John A. McLean 12.
High-Resolution Tandem Mass Spectrometry for Nonribosomal Peptide and
Polyketide Analysis 433 Rebecca H. Wills, Manuela Tosin, and Peter B.
O'Connor 13. Natural Product Drug Discovery and Analysis Using Mass
Spectrometry and Affinity-Based Technologies 475 Evelyn H. Wang and Kevin
A. Schug 14. Glycosylated Ribosomally Synthesized Peptide Toxins:
Discovery, Characterization, and Applications 507 Gillian E. Norris and
Mark L. Patchett 15. Using Ultrahigh-Resolution Mass Spectrometry to
Unravel the Chemical Space of Complex Natural Product Mixtures 545
Constanze Müller, Mourad Harir, Norbert Hertkorn, Basem Kanawati, Dimitrios
Tziotis, and Philippe Schmitt-Kopplin 16. Functional Amyloid Fibrils:
Lessons from Microbes 571 Sally L. Gras and Dennis Claessen Index 601