Mast Cells and Basophils (eBook, PDF)

Development, Activation and Roles in Allergic / Autoimmune Disease
Redaktion: Chadwick, Derek J.; Goode, Jamie A.

• Format: PDF

Produktbeschreibung

The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic possibilities for the treatment of diseases such as allergic inflammation and autoimmune disease which are mediated, in part, by these granulocytes.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 274
• Erscheinungstermin: 4. Januar 2006
• Englisch
• ISBN-13: 9780470030516
• Artikelnr.: 37289613

Autorenporträt

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.

Inhaltsangabe

Symposium on Mast cells and basophils: development
activation and roles in allergic/autoimmune disease
held at the Novartis Foundation
London
16-18 November 2004 Editors: Derek J. Chadwick (Organizer) and Jamie Goode This symposium was based on a proposal made by Santa Jeremy Ono. Santa Jeremy Ono: Chair's Introduction. Yukihiko Kitamura MITF and SgIGSF: an essential transcription factor and its target adhesion molecule for development and survival of mast cells Discussion. Paul J. Bryce
Mendy L. Miller
Ichiro Miyajima
Mindy Tsai
Stephen J. Galli and Hans C. Oettgen: Immune sensitization in the skin is enhanced by antigen-independent effects of IgE on mast cells Discussion. Yasuko Furumoto
Gregorio Gomez
Claudia Gonzalez-Espinosa
Martina Kovarova
Sandra Odom
John J. Ryan and Juan Rivera: The role of Src family kinases in mast cell effector function Discussion. Richard L. Stevens
Nasa Morokawa
Jing Wang and Steven A. Krilis: RasGRP4 in mast-cell signalling and disease susceptibility Discussion. J. Abramson
E. A. Barbu and I. Pecht: Regulation of mast cell secretory response to the type I Fce receptor: inhibitory elements and desensitization Discussion. General discussion I. Toshiaki Kawakami
Jiro Kitaura
Wenbin Xiao and Yuko Kawakami: IgE regulation of mast cell survival and function Discussion. See-Ying Tam
Janet Kalesnikoff
Susumu Nakae
Mindy Tsai and Stephen J. Galli: RabGEF1
a negative regulator of Ras signalling
mast cell activation and skin inflammation Discussion. Masako Toda
Takao Nakamura
Masaharu Ohbayashi
Yoshifumi Ikeda
Maria Dawson
Ricardo Micheler Richardson
Andrew Alban
Benjamin Leed
Dai Miyazaki and Santa Jeremy Ono: Role of CC chemokines and their receptors in multiple aspects of mast cell biology: comparative protein profiling of FceRI- and/or CCR1-engaged mast cells using protein chip technology Discussion. General discussion II. Shigeo Koyasu
Akiko Minowa
Yasuo Terauchi
Takashi Kadowaki and Satoshi Matsuda: The role of phosphoinositide-3-kinase in mast cell homing to the gastrointestinal tract Discussion. K. Frank Austen: The mast cell and the cysteinyl leukotrienes Discussion. Silvia Monticelli
K. Mark Ansel
Dong U. Lee and Anjana Rao: Regulation of gene expression in mast cells: micro-RNA expression and chromatin structural analysis of cytokine genes Discussion. Cellina Cohen-Saidon and Ehud Razin: The involvement of Bcl-2 in mast cell apoptosis Discussion. General discussion III. P. A. Nigrovic and D. M. Lee: Mast cells in autoantibody responses and arthritis Discussion. Greg D. Gregory
Allison Bickford
Michaela Robbie-Ryan
Mindy Tanzola and Melissa A. Brown: MASTering the immune response: mast cells in autoimmunity Discussion. Dean D. Metcalfe: Mastocytosis Discussion. Index of Contributors. Subject Index.

Rezensionen

"This is an excellent resource for clinicians or basic scientists with an interest in mast cells and related diseases." ( Doody s Health Services )