Glycosaminoglycans in Development, Health and Disease (eBook, PDF)

• Format: PDF

Produktbeschreibung

Glycosaminoglycans (GAGs) are a family of linear polysaccharides that are found in all animal tissues. Several are used as biomaterials, including heparin, heparin sulfate, keratan sulfate, dermatan sulfate, and chondroitin sulfate.

This volume discusses the role of GAGs in development, health and disease.

• This series provides a forum for discussion of new discoveries, approaches, and ideas
• Contributions from leading scholars and industry experts
• Reference guide for researchers involved in molecular biology and related fields

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 408
• Erscheinungstermin: 28. Oktober 2010
• Englisch
• ISBN-13: 9780123812834
• Artikelnr.: 38015865

Inhaltsangabe

1. Mice deficient in heparan sulfate N-sulphotransferase-1


Lena Kjellén and Maria Ringvall


2. Mice deficient in heparan sulfate epimerase


Jin ping Li


3. Mice deficient in heparan sulfate 3-O-sulfotransferase-1 Nicholas W. Shworak



4. Mice deficient in heparan sulfate 6-O-sulfotransferase-1


Koji Kimata and Hiroko Habuchi


5. Mice deficient in dermatan sulfate Epimerase


Marco Maccarana and Anders Malmström


6. The roles of chondroitin-4-sulfotransferase-1 in development and disease


Michael Klüppel


7. Conditionally disrupted EXT1 in the embryonic mouse brain.


Yu Yamaguchi


8. Endothelial heparan sulfate in inflammation


Jeffrey D. Esko and Ding Xu


9. Endothelial heparan sulfate in angiogenesis


Jeffrey D. Esko, Mark M. Fuster and Lianchun Wang


10. Hepatocyte heparan sulfate and lipoprotein metabolism


Jeffrey D. Esko and Erin Foley


11. Serglycin proteoglycan deletion in mouse platelet


Barbara P. Schick


12. GAGs in Amyloidosis


Jin ping Li and Xiao Zhang


13. Selectins, Heparins and Tumor Metastasis


Lubor Borsig


14. Chondroitin sulfate and Rheumatoid arthritis


Lijuan Zhang


15. Adducted thumb-clubfoot syndrome (ACTS) and Loss of dermatan-4-sulfotransferase 1 function


Jacques U Baenziger,Thomas Müller, Andreas Janecke and Lijuan Zhang


16. Vascular dermatan sulfate and heparin cofactor II


Douglas M. Tollefsen


17. Diverse Functions of Glycosaminoglycans in Infectious Diseases


Pyong Woo Park, Rafael Aquino, and Eui Seung Lee


18. Lessons learned from contaminated heparin. 1: Molecular mechanism underlines heparin induced thrombocytopenia and thrombosis.


Lijuan Zhang


19. Lessons learne from contaminated heparin. 2: Contact System Activation-induced Thrombin in Unrelated Human Thromboembolic Diseases

Lijuan Zhang, Peter Weiser, Yi Qian and Jing Pan

Rezensionen

PRAISE FOR THE SERIES:
"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal