Hans J. Ten Donkelaar, Martin Lammens, Akira Hori

Clinical Neuroembryology (eBook, PDF)

Development and Developmental Disorders of the Human Central Nervous System

• Format: PDF

Produktbeschreibung

This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental, and hypoxic/ischemic causes. The introductory chapters give an overview of the development of the human brain and the spinal cord, the mechanisms of development as obtained in experimental studies of various invertebrates and vertebrates, and the causes of congenital malformations. In the main part, the developmental disorders of the human brain and the spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These are underlined by carefully chosen clinical case studies, including imaging data and, when available, postmortem verification of the developmental disorders involved. Numerous color photographs and illustrations complement the text.

This second edition emphasizes the prenatal diagnosis by ultrasound, MRI, and DTI and implements new classifications of developmental disorders.

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Produktdetails

• Verlag: Springer-Verlag GmbH
• Seitenzahl: 659
• Erscheinungstermin: 16. Juni 2014
• Englisch
• ISBN-13: 9783642546877
• Artikelnr.: 43785702

Autorenporträt

Hans J. ten Donkelaar (1946) studied Medicine at the University of Nijmegen (The Netherlands), where he received his M.D. (1974) and Ph.D. (1975). In 1978, he was appointed Associate Professor of Neuroanatomy at the Department of Anatomy and Embryology of that University. His research interests are developmental and comparative aspects of motor systems, developmental disorders of the CNS and neurodegenerative diseases. With Rudolf Nieuwenhuys and Charles Nicholson he published The Central Nervous System of Vertebrates (1998, Springer) and with Anthony Lohman an anatomy and embryology textbook in Dutch, which is now in its fourth edition (BSL/Springer Media, Houten, NL, 2014). In 1998, he came to the Department of Neurology of the Radboud University Medical Centre to do research on developmental and neurodegenerative diseases. With Martin Lammens and Akira Hori he published Clinical Neuroembryology: Development and developmental disorders of the human central nervoussystem (2006, Springer; 2nd edition: 2014). In 2011, he published Clinical Neuroanatomy: Brain circuitry and its disorders (Springer; 2nd edition: 2020). Martin Lammens (1956) studied Psychology and Medicine at the University of Leuven (Belgium), where he received his M.D. in 1981. He specialized in Neurology, Psychiatry, General Pathology and Neuropathology in Aachen, Leuven and Brussels. He received his Ph.D. in 1997 on developmental neuropathology. He worked as consultant pathologist and neuropathologist at the Radboud University Medical Centre and at Maastricht University Hospital, and as Guest Professor of Neuropathology at the University of Gent (Belgium). In 2012, he was appointed Head of the Department of Pathology at the University Hospital Antwerp, Belgium. Currently, he is Consultant in Neuropathology at this hospital and several other Belgian Universities, and President of EURO-CNS. Akira Hori (1941) studied Medicine atthe Nagoya City University (Japan), where he received both his M.D. and Ph.D. After training in Neurology and Psychiatry in Nagoya (1967-1971), he went to Germany to study Neuropathology in Marburg (1971-1973), came back to Japan to the Department of Neuropathology of the Tokyo Institute of Psychiatry, and returned to Germany, at first to the Brain Research Institute of the University Tübingen (1977-1978), then Institute of Neuropathology in Göttingen (1978-1987), further as Professor of Neuropathology at the Hanover Medical School (1987-2004). He contributed to Pathologie - Neuropathologie (in German), now in its fourth edition (2012, Springer). In 2004, he was appointed Head of the Department of Clinical Research at the Tottori Medical Centre (Japan) and in 2006, he went to the Research Institute for Longevity Medicine, Fukushimura Hospital, Toyohashi (Japan). Currently, he is Guest Professor of Neuropathology at the Hanover Medical School andat the Ludwig-Maximilian-University Munich (Germany).

Inhaltsangabe

Overview of the Development of the Human Brain and Spinal Cord.- Mechanisms of Development.- Causes of Congenital Malformations.- Neurulation and Neurulation Defects.- The Neural Crest and Craniofacial Malformations.- Development and Developmental Disorders of the Spinal Cord.- Development and Developmental Disorders of the Brain Stem.- Development and Developmental Disorders of the Human Cerebellum.- Development and Developmental Disorders of the Forebrain.- Development and Developmental Disorders of the Cerebral Cortex.