Wang

Analysis of Complex Diseases (eBook, PDF)

A Mathematical Perspective

• Format: PDF

Produktbeschreibung

A complex disease involves many etiological and risk factors operating at multiple levels-molecular, cellular, organismal, and environmental. The incidence of such diseases as cancer, obesity, and diabetes are increasing in occurrence, urging us to think fundamentally and use a broader perspective to identify their connection and revolutionize trea

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 222
• Erscheinungstermin: 18. Dezember 2013
• Englisch
• ISBN-13: 9781466572232
• Artikelnr.: 40391644

Autorenporträt

Guanyu Wang obtained one PhD (in engineering) from Zhejiang University, China, in 1998 and one PhD (in medical sciences) from the University of Cologne, Germany, in 2005. As a postdoctoral fellow, he was initially at the School of Health Information of the University of Texas Health Science Center at Houston and then at the Department of Bioengineering, Rice University. He was an assistant professor of Pathology and Laboratory Medicine at the University of Texas Health Science Center at Houston and then an assistant professor of Physics at George Washington University. He is now an associate professor of biology at South University of Science and Technology of China, located in the city of Shenzhen.

Inhaltsangabe

Organismal Level: What Is Required. Food Intake and Energy Metabolism.
Glucose Homeostasis. Optimal Glucose Homeostasis. Bistability as a
Fundamental Phenomenon. Molecular Level: What Can Be Provided? Molecular
Biology. Biomolecular Network. PI3K-AKT-TOR Pathway. Mathematical Analysis
of Complex Diseases. Diseases Related to Metabolism. Mathematical Modeling
of the PI3K-AKT-TOR Pathway. Fundamental Decomposition. Normal Phenotype.
Disease Phenotypes. Tao of Diseases. References. Abbreviations. Appendix A
Optimization of Insulin Action. Appendix B Derivation of the Master
Equation of AKT Activation. Appendix C Singularity Theory. Appendix D
Analysis of the Simplified Master Equation. Appendix E Analysis of the
Master Equation. Index.