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High Quality Content by WIKIPEDIA articles! Ventilator-associated pneumonia (VAP) is a sub-type of hospital-acquired pneumonia (HAP) which occurs in people who are on mechanical ventilation through an endotracheal or tracheostomy tube for at least 48 hours. VAP is a medical condition that results from infection which floods the alveoli - small, air-filled sacs in the lung responsible for absorbing oxygen from the atmosphere.