The nameless and beautiful woman appears to be just another corpse in the morgue. An apparent suicide, she lies on a gurney in the cold room, awaiting the dissecting scalpel of medical examiner Maura Isles. But when Maura unzips the body bag and looks down at the body, she gets the fright of her life. The corpse opens its eyes. Now very much alive, the "dead" woman is rushed to the hospital where her next action shocks everyone. With cool precision, she murders a security guard and seizes hostages. One of those hostages is a very pregnant patient - Jane Rizzoli. Who is this mysterious hostage-taker, and what does she want? As tense hours tick by, Maura joins forces with Jane's husband, FBI agent Gabriel Dean, to track down the nameless woman's identity. When Federal agents suddenly appear on the scene, Maura and Gabriel realize they are dealing with a case that goes far deeper than just an ordinary hostage crisis. Only Jane, trapped with the armed madwoman, holds the key to the mystery. And only she can solve it - if she survives the night.