The Unfolded Protein Response and Cellular Stress, Part C

Volume 491
Herausgegeben:Conn, P. Michael

• Gebundenes Buch

Produktbeschreibung

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights

Produktdetails

• Methods in Enzymology Volume 491
• Verlag: Academic Press / Elsevier Science & Technology
• Artikelnr. des Verlages: C2010-0-66908-2
• Seitenzahl: 464
• Erscheinungstermin: 25. Februar 2011
• Englisch
• Abmessung: 239mm x 161mm x 30mm
• Gewicht: 890g
• ISBN-13: 9780123859280
• ISBN-10: 012385928X
• Artikelnr.: 32927768

Inhaltsangabe

Section I: New Approaches to Studying UPR and Cell Stress

1. CFTR Expression Regulation by the Unfolded Protein Response Rafal Bartoszewski, Andras Rab, Lianwu Fu, Sylwia Bartoszewska, James Collawn and Zsuzsa Bebok
2. GRP78/BiP Chapter: Modulation of GRP78/BiP in Altering Sensitivity to Chemotherapy Thomas C. Chen
3. Targeting the Unfolded Protein Response in Cancer Therapy Marina V. Backer, Joseph M. Backer & Prakash Chinnaiyan
4. Large-scale analysis of UPR-mediated apoptosis in human cells Andrew M. Fribley, Justin R. Miller, Tyler E. Reist¹, Michael U. Callaghan and Randal J. Kaufman
5. Quantitative Analysis of amino acid oxidation markers by tandem mass spectrometry Anuradha Vivekanandan-Giri, Jaeman Byun and Subramaniam Pennathur
6. Animal models in the study of the unfolded protein response Hemamalini Bommiasamy and Brian Popko
7. Measurement of Fluoride-induced Endoplasmic Reticulum Stress Using Gaussia luciferase Ramaswamy Sharma, Masahiro Tsuchiya, Bakhos A. Tannous and John D. Bartlett
8. Analysis of nelfinavir-induced endoplasmic reticulum stress Ansgar Brüning
9. Using temporal genetic switches to synchronize the unfolded protein response in cell populations in vivo Alexander Gow
10. Glycoprotein maturation and the UPR Andreas J. Hülsmeier, Michael Welti and Thierry Hennet
11. Monitoring and Manipulating Mammalian Unfolded Protein Response Nobuhiko Hiramatsu, Victory T. Joseph and Jonathan H. Lin
12. A screen for mutants requiring activation of the unfolded protein response for viability Guillaume Thibault and Davis T.W. Ng
13. Signalling Pathways of Proteostasis Network Unrevealed By Proteomic Approaches on The Understanding of Misfolded Protein Rescue Patrícia Gomes-Alves, Sofia Neves and Deborah Penque
14. Decreased Secretion and Unfolded Protein Response Up-Regulation Carissa L. Young, Theresa Yuraszeck, Anne S. Robinson
15. Measuring signaling by the unfolded protein response David Cox, Natalie Strudwick, Ahmed A. Ali, Adrienne W. Paton, James C. Paton, and Martin Schröder
16. Unfolded Protein Response Jie Shang
17. Regulation of immunoglobulin synthesis, modification and trafficking by the unfolded protein response: a quantitative approach Adi Drori and Boaz Tirosh
18. Use of Chemical Genomics in Assessment of the UPR Sakae Saito, Akihiro Tomida
19. Small GTPase signalling and the Unfolded Protein Response Marion Bouchecareilh, Esther Marza, Marie-Elaine Caruso and Eric Chevet
20. Inhibitors of advanced glycation and endoplasmic reticulum stress Reiko Inagi