Sumeer Chadha

The Prefrontal - Hippocampal Pathway and Behavioural Inhibition

Transient Lesions of the Prefrontal Cortex Result in a Decrease in Behavioural Inhibition in Rats in the Place-pref Task

• Broschiertes Buch

Produktbeschreibung

Behavioural inhibition is the ability to suppress irrelevant behaviours that are either unsafe or are inappropriate for the task at hand. Neuropsychological studies have linked behavioural inhibition primarily to the actions of the medial prefrontal cortex, the hippocampus, as well as several additional regions of the brain. The current investigation addressed the role of the mPFC-hippocampal pathway on behavioural inhibition within the place-preference task. Muscimol, a GABA-A agonist, was used to create a transient block of the prelimbic cortex within the mPFC to examine its effects on both behaviour and on hippocampal electrophysiology in rats. The rationale for this line of inquiry stems from a growing body of research purporting a link between the mPFC and the HPC in terms of theta-coordinated communication between the two regions during mnemonic tasks.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Aufl.
• Seitenzahl: 68
• Erscheinungstermin: 13. Dezember 2011
• Englisch
• Abmessung: 220mm x 150mm x 5mm
• Gewicht: 119g
• ISBN-13: 9783847317821
• ISBN-10: 3847317822
• Artikelnr.: 34635439

Autorenporträt

He earned a B.A. in Psychology from McDaniel College, USA in 2003, an M.A. in Psychology from the University of Mississippi, USA in 2010, and an M.Sc. in Pyschology, from Otago University, Dunedin NZ. As of October, 2011, he has been participating in research on cognition and psycholinguistics at the University of Pompeu Fabra, Barcelona, Spain