Proteinase and Peptidase Inhibition

Herausgeber: Smith, H John; Simons, Claire

• Broschiertes Buch

Produktbeschreibung

Cellular proteinases and their physiological role in normal and disease states have been the subject of great interest recently. Proteinase and Peptidase Inhibition presents new reports on a wide range of cellular proteinases whose inhibitors may hold the key to the development of new drugs. It deals with enzyme classes, inhibitor types and regulat

Produktdetails

• Verlag: CRC Press
• Seitenzahl: 436
• Erscheinungstermin: 2. Dezember 2019
• Englisch
• Abmessung: 246mm x 189mm x 23mm
• Gewicht: 776g
• ISBN-13: 9780367454982
• ISBN-10: 036745498X
• Artikelnr.: 58441473

Autorenporträt

Smith, H. John; Simons, Claire

Inhaltsangabe

Enzyme Classes and Mechanisms. Regulatory Mechanisms for Proteinase
Activity. Matrix Metalloproteinases (MMPs). Proteasomes. Cathepsins.
Calpain. Human Neutrophil Elastase Inhibitors. Thrombin. Inhibitors of
Factor VIIa, Factor IXa, and Factor Xa as Anticoagulants. The
Urokinase-Type Plasminogen Activator (uPA) System: A New Target for Tumor
Therapy. Proteinases Involved in Amyloid ß-Peptide (Aß) Production and
Clearance. Herpes Virus and Cytomegalovirus Proteinase. Human Rhinovirus 3C
Proteinase Inhibitors. Aminopeptidases. The Hepatitis C Virus NS3
Serine-Type Proteinase. Zinc Metallopeptidases. HIV Aspartate Proteinase:
Resistance to Inhibitors. Proteases of Protozoan Parasites for Proteinase
Activity.