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Analysis of the current level of integration of HIV and AIDS priorities into the macroeconomic process shows that these priorities are not taken into account in the national policy-making process. The presentation of the TOFE does not regularly show the amount of funds drained for the fight against the disease. The PRSP takes into account the response as a sub-component of the health sector and budget lines with very modest amounts are allocated. Most of the response activities are financed externally. The inclusion of the epidemic response priorities in the macroeconomic process is hampered by a poorly adapted statistical information system and other constraints such as insufficient financial and human resources and limited knowledge of the socio-economic consequences of the disease. A way of integrating the priorities of the fight against the epidemic into the macroeconomic process should be to capitalize on the data already available and to gain a better understanding of the economic and social consequences of HIV and AIDS by applying appropriate models.