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The ESPAUR (English Surveillance Programme for Antimicrobial Utilisation and Resisistance) national annual report 2021-2022 interactive online webinar held on Wednesday 23 November 2022, and a summary of key findings covering each chapter is presented. The chapters include Antimicrobial Resistance; Antimicrobial Consumption; Antimicrobial Stewardship; NHS England: Improvement and Assurance Schemes; Professional and Public Education, Engagement and Training; COVID-19 Therapeutics; Research; and Stakeholder Engagement. The Antibiotic Guardian Shared Learning and Awards (AGSLA) event, which acknowledges, celebrates, and provides opportunity for shared learning from the work of healthcare professionals across the UK and abroad in tackling antimicrobial resistance.