This book focuses on the modern approach to the isolation of biologically active natural products and provides numerous examples of the isolation and characterization of secondary metabolites. It emphasizes the synthetic or semi-synthetic analogues of natural products, relevant to those working on biomedical applications of natural products. It includes chapters on general methods together with more specific chapters discussing the main topics in the field, including important families or properties of bioactive natural products, synthesis of analogues, biological evaluation of both natural…mehr
This book focuses on the modern approach to the isolation of biologically active natural products and provides numerous examples of the isolation and characterization of secondary metabolites. It emphasizes the synthetic or semi-synthetic analogues of natural products, relevant to those working on biomedical applications of natural products. It includes chapters on general methods together with more specific chapters discussing the main topics in the field, including important families or properties of bioactive natural products, synthesis of analogues, biological evaluation of both natural and synthetic products, and structure-activity relationship studies.
Professor Corrado Tringali obtained his BA in chemistry at the University of Catania, Italy, in 1973. From 1977 to 1985 he was an assistant professor, teaching courses in organic chemistry and physical methods in organic chemistry. In November 1985 he became an associate professor (organic chemistry), and since November 2001 he has been a full professor (teaching courses in organic chemistry, natural products chemistry, and physical methods in organic chemistry). At present, he is coordinator of the international Doctorate of Research in Chemical Science program at the University of Catania (Cycles XXII -XIV).
Inhaltsangabe
Strategies and Methods for a Sustainable Search for Bioactive Compounds. Discovery of Potential Anticancer Agents from Aquatic Cyanobacteria, Filamentous Fungi, and Tropical Plants. Metabolic Engineering of Natural Product Biosynthesis. Computational Approaches for the Discovery of Natural Lead Structures. Recent Advances in the Application of Electronic Circular Dichroism for Studies of Bioactive Natural Products. Natural Products as Treatments for and Leads to Active Compounds in Viral Diseases. Natural Products as Inhibitors of Hypoxia-Inducible Factor-1 (HIF-1). From Antitumor or Wound Healing Actions of Natural Products through Angiogenesis. From Natural Polyphenols to Synthetic Antitumor Agents. Resveratrol against Major Pathologies: From Diet Prevention to Possible Alternative Chemotherapies with New Structural Analogues. Drug Discovery from Natural Substances-A Case Study: Camptothecins. Plant Compounds and Derivatives as Inhibitors of Cancer Cell Multidrug Resistance. Recent Advances in the Search of Novel Calmodulin Inhibitors from Selected Mexican Plants and Fungi. Neuroprotective Effects of Natural Products from Traditional Chinese Herbs. Drugs for the Neglected Disease Malaria based on Natural Products. Endophytic Microorganisms as a Source of Bioactive Compounds. Biologically Active Natural Products from Australian Marine Organisms.
Strategies and Methods for a Sustainable Search for Bioactive Compounds. Discovery of Potential Anticancer Agents from Aquatic Cyanobacteria, Filamentous Fungi, and Tropical Plants. Metabolic Engineering of Natural Product Biosynthesis. Computational Approaches for the Discovery of Natural Lead Structures. Recent Advances in the Application of Electronic Circular Dichroism for Studies of Bioactive Natural Products. Natural Products as Treatments for and Leads to Active Compounds in Viral Diseases. Natural Products as Inhibitors of Hypoxia-Inducible Factor-1 (HIF-1). From Antitumor or Wound Healing Actions of Natural Products through Angiogenesis. From Natural Polyphenols to Synthetic Antitumor Agents. Resveratrol against Major Pathologies: From Diet Prevention to Possible Alternative Chemotherapies with New Structural Analogues. Drug Discovery from Natural Substances-A Case Study: Camptothecins. Plant Compounds and Derivatives as Inhibitors of Cancer Cell Multidrug Resistance. Recent Advances in the Search of Novel Calmodulin Inhibitors from Selected Mexican Plants and Fungi. Neuroprotective Effects of Natural Products from Traditional Chinese Herbs. Drugs for the Neglected Disease Malaria based on Natural Products. Endophytic Microorganisms as a Source of Bioactive Compounds. Biologically Active Natural Products from Australian Marine Organisms.
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