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Human plasma contains the most comprehensive version of the human proteome. The complexity of the 'plasma proteome' is quickly understood when one considers all the various forms of blood plasma proteins present in plasma: precursor and mature forms, splice variants, degradation products and of course all combinations of posttranslational modifications.
Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include: Introduction to
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Produktbeschreibung
Human plasma contains the most comprehensive version of the human proteome. The complexity of the 'plasma proteome' is quickly understood when one considers all the various forms of blood plasma proteins present in plasma: precursor and mature forms, splice variants, degradation products and of course all combinations of posttranslational modifications.

Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include:
Introduction to blood components and blood plasma proteins
Blood plasma protein domains, motifs and repeats
Blood plasma protein families and posttranslational modifications
Blood coagulation and fibrinolysis
The complement system
The immune system
Enzymes
Inhibitors
Lipoproteins
Hormones
Cytokines and growth factors
Transport and storage

The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure.

Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.
Autorenporträt
Johann Schaller and Simon Gerber are the authors of Human Blood Plasma Proteins: Structure and Function, published by Wiley.