Viral Vectors in Cancer Immunotherapy (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Viral Vectors in Cancer Immunotherapy, Volume 379 in the International Review of Cell and Molecular Biology presents the latest on cancer immunotherapy and how it has transformed cancer treatment through advances in immune checkpoint inhibitors and adoptive cell therapy. Chapters in this new release include Past, present and future of viral vectors in cancer immunotherapy, Alphaviruses in cancer immunotherapy, Adenoviral-based cancer gene therapy, Armored modified vaccinia Ankara in cancer immunotherapy, Strategies of Semliki Forest virus in immuno-oncology, Maraba virus in cancer immunotherapy, Oncolytic viruses in hematological malignancies, Oncolytic virus for cancer therapies: Overview and future directions, and more.

The use of genetically modified viruses allows the expression of pro-inflammatory molecules, while the immune system receives danger signals from the viruses themselves. In some cases, the virus can also induce tumor cell death. This book will review advances in virus-based cancer immunotherapy in both solid tumors and hematologic malignancies.

• Provides an overview of the landscape of virotherapy for solid tumors and hematologic malignancies
• Reviews advances in alphaviruses, adenoviruses, vaccinia viruses and Maraba virus
• Presents lessons on how to improve viruses to enhance immune responses

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 277
• Erscheinungstermin: 2. August 2023
• Englisch
• ISBN-13: 9780443192500
• Artikelnr.: 68530072

Inhaltsangabe

1. Viral Vectors Engineered for Gene Therapy
Kenneth Lundstrom
2. Checkpoint blockade meets gene therapy: Opportunities to improve
response and reduce toxicity
Noelia Silva-Pilipich, Ángela Covo-Vergara, Lucía Vanrell, and Cristian
Smerdou
3. Armored modified vaccinia Ankara in cancer immunotherapy
Cigdem Atay, José Medina-Echeverz, Hubertus Hochrein, Mark Suter, and Maria
Hinterberger
4. Alphaviruses in Cancer Immunotherapy
Kenneth Lundstrom
5. Oncolytic viruses as treatment for adult and pediatric high-grade
gliomas: On the way to clinical success
Irati Hervás-Corpión and Marta M. Alonso
6. Oncolytic viruses in hematological malignancies: hijacking disease
biology and fostering new promises for immune and cell-based therapies
Mário Sousa-Pimenta, Ângelo Martins, and Vera Machado
7. Oncolytic virotherapy in lung cancer
Estanislao Nistal-Villan, Sergio Rius-Rocabert, and Francisco
Llinares-Pinel
8. Rational selection of an ideal oncolytic virus to address current
limitations in clinical translation
Rupsa Basu and Chad M. Moles