Viral Replication Enzymes and their Inhibitors Part A (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Viral Replication Enzymes and their Inhibitors Part A, Volume 49, the latest release in the Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of related topics.

• Provides the authority and expertise of leading contributors from an international board of authors
• Presents the latest release in The Enzymes series

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 368
• Erscheinungstermin: 23. Oktober 2021
• Englisch
• ISBN-13: 9780128234693
• Artikelnr.: 62828787

Autorenporträt

Craig E. Cameron is at UNC School of Medicine, NC, USAJamie J. Arnold is at UNC School of Medicine, Chapel Hill, NC, USA

Inhaltsangabe

Preface



Craig E. Cameron, Jamie J. Arnold and Laurie S. Kaguni



1. CoV-er all the bases: Structural perspectives of SARS-CoV-2 RNA synthesis



Brandon Malone, Seth A. Darst and Elizabeth A. Campbell



2. Mechanisms of inhibition of viral RNA replication by nucleotide analogs



Kenneth A. Johnson and Tyler Dangerfield



3. HCV RdRp, sofosbuvir and beyond



Joy Y. Feng and Adrian S. Ray



4. Understanding viral replication and transcription using single-molecule techniques



Emmanuelle Pitre and Aartjan J.W. te Velthuis



5. In vitro single-molecule manipulation studies of viral DNA replication



Rebeca Bocanegra, Ismael Plaza-G.A. and Borja Ibarra



6. Allosteric and dynamic control of RNA-dependent RNA polymerase function and fidelity



Dennis S. Winston and David D. Boehr



7. Single-cell analysis for the study of viral inhibitors



Mohamad S. Sotoudegan, Jamie J. Arnold and Craig E. Cameron



8. Structural basis of viral RNA-dependent RNA polymerase nucleotide addition cycle in picornaviruses



Peng Gong



9. Picornaviral 2C proteins: A unique ATPase family critical in virus replication



Pu Chen, Zhijian Li and Sheng Cui



10. Flavivirus enzymes and their inhibitors



Ekaterina Knyazhanskaya, Marc C. Morais and Kyung H. Choi



11. Watching the bacterial RNA polymerase transcription reaction by time-dependent soak-trigger-freeze X-Ray crystallography



Yeonoh Shin and Katsuhiko S. Murakami



12. Inhibition of viral RNA-dependent RNA polymerases with clinically relevant nucleotide analogs



Kieran Maheden, Brendan Todd, Calvin J. Gordon, Egor P. Tchesnokov and Matthias Götte