Transport Processes in Pharmaceutical Systems (eBook, PDF)

Redaktion: Amidon, Gordon L.; Topp, Elizabeth M.; Lee, Ping I.

• Format: PDF

Produktbeschreibung

This cutting-edge reference clearly explains pharmaceutical transport phenomena, demonstrating applications ranging from drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes, whole body kinetics, and drug release from polymer reservoirs and matrices to heat and mass transport in freeze-drying and hygroscopicity.
Focuses on practical applications of drug delivery from a physical and mechanistic perspective, highlighting biological systems.
Written by more than 30 international authorities in the field, Transport Processes in Pharmaceutical Systems

discusses the crucial relationship between the transport process and thermodynamic factors

analyzes the dynamics of diffusion at liquid-liquid, liquid-solid, and liquid-cultured cell interfaces

covers prodrug design for improving membrane transport

addresses the effects of external stimuli in altering some natural and synthetic polymer matrices

examines properties of hydrogels, including synthesis, swelling degree, swelling kinetics, permeability, biocompatibility, and biodegradability

presents mass transfer of drugs and pharmacokinetics based on mass balance descriptions

and more!
Containing over 1000 references and more than 1100 equations, drawings, photographs, micrographs, and tables, Transport Processes in Pharmaceutical Systems is a must-read resource for research pharmacists, pharmaceutical scientists and chemists, chemical engineers, physical chemists, and upper-level undergraduate and graduate students in these disciplines.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 748
• Erscheinungstermin: 24. November 1999
• Englisch
• ISBN-13: 9780203909478
• Artikelnr.: 38167452

Autorenporträt

Gordon L. Amidon, Ping I. Lee, Elizabeth M. Topp

Inhaltsangabe

Introduction to Transport Processes Principles of Mass Transfer Elizabeth
M. Topp Analytical Solutions to Mass Transfer Lawrence X. Yu and Gordon L.
Amidon Pharmacokinetics: Model Structure and Transport Systems James M.
Gallo Experimental Methods to Evaluate Diffusion Coefficients and
Investigate Transport Processes of Pharmaceutical Interest John W. Mauger
Dissolution of Pharmaceuticals in Simple and Complex Systems Daniel P.
McNamara, Michael L. Vieira, and John R. Crison Biological Transport
Processes Biological Transport Phenomena in the Gastrointestinal Tract:
Cellular Mechanisms David Fleisher Improving Oral Drug Transport via
Prodrugs Mandana Asgharnejad Quantitative Approaches to Delineate Passive
Transport Mechanisms in Cell Culture Monolayers Norman F. H. Ho, Thomas J.
Raub, Phillip S. Burton, Craig L. Barsuhn, Anthony Adson, Kenneth L. Audus,
and Ronald T. Borchardt Barriers to Drug Transport in Ocular Epithelia Uday
B. Kompella and Vincent H. L. Lee Predicting Oral Drug Absorption in Humans
Lawrence Yu, Larry Gatlin, and Gordon L. Amidon Transport Processes in
Polymer Systems Controlled Release Osmotic Drug Delivery Systems for Oral
Applications John R. Cardinal Transport in Polymer Systems Jim H. Kou
Synthesis and Properties of Hydrogels Used for Drug Delivery Stevin H.
Gehrke Stimuli-Modulated Delivery Systems Sung Wan Kim and You Han Bae
Properties of Solids that Affect Transport Manesh J. Nerurkar, Sarma Duddu,
David J. W. Grant, and J. Howard Rytting Heat and Mass Transport Heat and
Mass Transfer in Low Pressure Gases: Applications to Freeze Drying Michael
J. Pikal Heat and Mass Transport: Hygroscopicity James Wright