Ioannis V. Yannas

Tissue and Organ Regeneration in Adults (eBook, PDF)

Extension of the Paradigm to Several Organs

• Format: PDF

Produktbeschreibung

This textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation. New to this second edition: New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties The work serves as a comprehensive text and reference for students and practitioners of tissue engineering

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Produktdetails

• Verlag: Springer-Verlag GmbH
• Seitenzahl: 332
• Erscheinungstermin: 21. November 2014
• Englisch
• ISBN-13: 9781493918652
• Artikelnr.: 43794335

Autorenporträt

Dr. Ioannis V. Yannas is a professor of Mechanical and Biological Engineering at MIT.

Inhaltsangabe

The Irreversibility of Organ Injury.- Nonregenerative Tissues.- Experimental Methods I. The Anatomically Well-Defined Wound.- Experimental Methods II. The Defect Closure Rule.- Regeneration of Skin.- Regeneration of a Peripheral Nerve.- Minimum Reactants Required for Synthesis of Skin and Peripheral Nerves; Extension to Tissues of Other Organs.- An Antagonistic Relation Between Wound Contraction and Regeneration.- Molecular biology of contraction blockade by active scaffolds.- The Scaffold Regeneration Paradigm and its Consequences.