Proteomics Approaches to Unravel Virus - Vertebrate Host Interactions (eBook, PDF)

• Format: PDF

Produktbeschreibung

Proteomics Approaches to Unravel Virus - Vertebrate Host Interactions, Volume 109 in the Advances in Virus Research series, highlights state-of-the art mass spectrometry techniques to elucidate the tight interplay of vertebrate viruses and their host cells. The volume includes chapters on Spatio-temporal resolution of host protein complexes during virus entry, Proteomic approaches to investigate gammaherpesvirus biology and associated tumorigenesis, Applications of Mass Spectrometry Imaging in Virus Research, Mapping surfaceome dynamics during viral infection, Characterization of proteolytic events in virus-host interactions, Dynamic protein network modulation upon viral infection, and much more.

• Discusses the latest methodological breakthroughs in mass spectrometry-based proteomics
• Reviews how technology has advanced our knowledge on virus-host interactions
• Provides future perspectives on proteomics research in virology

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 264
• Erscheinungstermin: 30. April 2021
• Englisch
• ISBN-13: 9780128230404
• Artikelnr.: 61690457

Autorenporträt

Dr. Gisa Gerold accomplished her graduate research at the Max Planck Institute for Infection Biology, Berlin, Germany, under the supervision of Arturo Zychlinsky. She pursued her postdoctoral work in the laboratory of Virology and Infectious Diseases of Charles M. Rice at The Rockefeller University, New York, NY. Currently, she is a professor for Molecular and Clinical Infection Research at the Institute for Biochemistry at the University of Veterinary Medicine Hannover, Germany. She further holds a Guest Associate Professor position at the Department of Clinical Microbiology and the Wallenberg Center for Molecular Medicine at Umea University, Sweden. Her joint German and Swedish research team focuses on elucidating pathogenic RNA virus infection from a proteomics perspective. With a particular focus on emerging zoonotic viruses and their interplay with the host cell at the protein level, her goal is to unravel mechanisms of pathogenesis, host and tissue tropism determinants and

key points of therapeutic intervention. By integrating proteomics techniques with cell biology, virology and big data science she strives to bridge the gap between virus and host genetics and a mechanistic understanding of virus infection in order to develop rapid response measures against newly emerging pathogens. Dr. Gerold received the Otto Hahn Medal of the Max Planck Society and the Robert Koch Society postdoctoral award in Virology. She is a member of the advisory board of the German Society for Virology (GfV).

Inhaltsangabe

1. Spatio-temporal resolution of host protein complexes during virus entry Francisco José Zapatero Belinchón 2. Chapter title to be confirmed Andreas Pichlmair 3. Proteomic approaches to investigate gammaherpesvirus biology and associated tumorigenesis Blossom A Damania 4. Applications of Mass Spectrometry Imaging in Virus Research Luca Danilo Bertzbach, Benedikt B. Kaufer and Axel Karger 5. Chapter title to be confirmed Ileana M. Cristea 6. Mapping surfaceome dynamics during viral infection Bernd Wollscheid 7. Characterization of proteolytic events in virus-host interactions Marjolein Kikkert 8. Chapter title to be confirmed Jason Mercer 9. Dynamic protein network modulation upon viral infection Christian Munch