Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU (eBook, ePUB)

Redaktion: Negro, Gianni Dal; Sabbioni, Silvia

• Format: ePub

Produktbeschreibung

Practical Handbook on the 3Rs in the Context of the Directive 2010/63/EU provides updated information on the EU Directive 2010/63/EU, which is the European Union legislation that protects animals being used in research. EU Directive 2010/63/EU is the European Union (EU) legislation 'on the protection of animals used for scientific purposes' and is one of the most stringent ethical and welfare standards worldwide.

• Closes a gap in scientific literature by addressing the need for clear guidance in walking through the multifaced universe of 3Rs
• Offers a useful starting point for readers and scientist who approach the 3Rs for the first-time
• Gives insights into the harmonization of the animal research legislation across countries

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 346
• Erscheinungstermin: 18. November 2021
• Englisch
• ISBN-13: 9780128212523
• Artikelnr.: 62948202

Autorenporträt

Dr. Gianni Dal Negro is an European Registered Toxicologist with over 30 years of experience in Research and Development applied to both the regulatory and non-regulatory areas in the pharmaceutical sector. In his career, he has represented the European Federation of Pharmaceutical Industries and Associations (EFPIA) in the ECVAM Scientific Advisory Committee (ESAC); he has been member of international committees and he has contributed to international initiatives relevant to the 3Rs (science, legislation, regulatory requirements). Before retiring, Dr. Dal Negro has been World-wide Director of 3Rs at GlaxoSmithKline Ltd, UK, Industry Chair of the European Partnership for Alternative Approaches to Animal Testing (EPAA), and member of the Royal College of Veterinary Surgeons in UK. He is past President of the Italian Association of Laboratory Animal Science (AISAL). Dr. Dal Negro has authored and co-authored several papers in peer-reviewed journals. He is also a member of the Editor

ial Board of the Journal Toxicology in Vitro (Elsevier).

Inhaltsangabe

1. Ethics and law on human-animal relationship
2. Communication and transparency in research involving animals
3. Anatomy, physiological features, genetics and genetic alterations, breeding and strain differences relevant to the choice of the model-Impact of 3Rs
4. Animal welfare
5. Methods of handling and procedures
6. Animal?health?management and hygiene
7. Recognition of pain, distress, and suffering
8. Harm to research animals, severity categories, and humane endpoints
9. Anaesthesia, analgesia, and killing
10. Replacement
11. Design of procedures and projects