John G. Wagner

Pharmacokinetics for the Pharmaceutical Scientist (eBook, ePUB)

• Format: ePub

Produktbeschreibung

A major presentation of pharmacokinetics by a leading international expert, this is a complete book on modeling the pharmacokinetics of drugs. It provides methods for: estimating drug disposition parameters from data obtained after intravascular or extravascular drug administration, estimating rate and extent of drug bioavailability, and comparing rate and extent of drug availability following administration of several different dosage forms of a drug. Authored by one of the founders of the field and written with insight that can only be obtained from years of experience, it is one of the very few advanced texts in the field.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 336
• Erscheinungstermin: 19. Dezember 2018
• Englisch
• ISBN-13: 9781351425117
• Artikelnr.: 54912773

Autorenporträt

Wagner, John G.

Inhaltsangabe

Simple Linear Models
More Complicated Linear Models
Complicated Linear Models
Linear Multicompartment Disposition Parameters from Extravascular Downslope
C,T Data
Noncompartmental and System Analysis Linear Multiple Dose Equations
Simple Nonlinear Models
More Complicated Nonlinear Models
Urinary Excretion
Absorption Analysis and Bioavailability
Physiological Pharmacokinetics
Relationship between Physiologically Based Flow Models and Usual
Compartment
Models
Protein Binding
Pharmacokinetic
Pharmacodynamic Modelling
Metabolic Kinetics
Laplace Derivation of Linear Pharmacokinetic Equations
Measures of Fit
Appendix
Index
175 Figures and Schematics, 51 Tables, 134 References