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Focusing on the redox regulation of cell signaling responsible for oxidative stress and inflammatory tissue damage, this reference presents a comprehensive overview of cutting-edge research on the intracellular events mediating or preventing oxidative stress and pro-inflammatory processes induced by endogenous and xenobiotic factors. It provides a mechanistic basis for cellular alterations by pro-oxidative and pro-inflammatory insults, introduces recent methods to combat oxidative stress and inflammatory damage, contains the latest studies on the regulation of gene expression by oxidants and antioxidants, and explores chemopreventive strategies targeting intracellular signaling.
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