Nucleic Acid Sensing and Immunity - PART B (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Nucleic Acid Sensing and Immunity - PART B, Volume 345 gives a comprehensive overview of the nucleic acid machinery, from plants to mammalians, along with their regulation. Chapters in this updated volume include Nucleic acids sensing in allergic disorders, Nucleic acids sensing in autoimmune disorders, Nucleic acid sensing in inflammatory disorders, Viral nucleic acid sensing inflammasomes in intestinal host defense, Genome damage sensing leads to tissue homeostasis in Drosophila, Nucleic acids sensing in plants, Nucleic Acid sensing in invertebrates, amongst other topics.

• Provides an accurate, state-of-the-art resource on RNA sensing
• Includes the work of a well-known tumor immunologist
• Links intestinal host defense and viral nucleic acid sensing
• Presents a chapter on the negative regulation of DNA sensing, a timely topic

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 374
• Erscheinungstermin: 21. März 2019
• Englisch
• ISBN-13: 9780128159828
• Artikelnr.: 56049603

Autorenporträt

Claire Vanpouille-Box received her Ph.D. in Experimental Pharmacology in 2011 from the University of Angers, France. Determined to pursue an academic career and intrigued by the emerging role of radiation in cancer immunotherapy, she decided to join the lab of Dr. Demaria in 2011 to conduct her postdoctoral training. Claire is currently holding a junior faculty position as an instructor in radiation oncology at Weill Cornell Medicine where she is focusing her research to study the mechanisms whereby radiation therapy can convert a tumor into an in situ individualized vaccine. In particular, Claire is leveraging her multidisciplinary background to better understand how radiation should be administered to induce anti-tumor immunity. She has published 28 articles in peer-reviewed scientific journals and have received many prestigious awards among which the 2014-Marie Curie Award from the Radiation Research Society (RRS), the 2015-AACR Susan G Komen Scholar-in-training award from the

American Association for Cancer Research (AACR) and the 2017-AAI Early Career Faculty travel grant from the American Association of Immunologists (AAI).

Inhaltsangabe

1. Nucleic acids sensing in allergic disorders James Gerard Martin 2. Nucleic acids sensing in autoimmune disorders Alan G. Goodman 3. Nucleic acid sensing in inflammatory disorders Hasan Zaki 4. Viral nucleic acid sensing inflammasomes in intestinal host defence Andy Wullaert 5. Genome damage sensing leads to tissue homeostasis in Drosophila BJ Rao 6. Nucleic acids sensing in plants Martin Heil 7. Nucleic Acid sensing in invertebrates Wang Pei-Hui