Non-Canonical Autophagy (eBook, PDF)

Mechanisms and Pathophysiological Implications
Redaktion: Petroni, Giulia; Galluzzi, Lorenzo

• Format: PDF

Produktbeschreibung

Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between 'canonical' and 'non-canonical' forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of 'non-canonical' autophagy. The book discusses all forms of 'non-canonical' autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying 'non-canonical' autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies.

• Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy
• Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes
• Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 182
• Erscheinungstermin: 21. April 2021
• Englisch
• ISBN-13: 9780128209110
• Artikelnr.: 61688628

Autorenporträt

Giulia Petroni is a PhD Fellow at the Department of Experimental and Clinical Medicine, University of Florence. Giulia does research in Oncology, focusing on the ion channels' role in Colorectal Cancer. She has also an expertise in Clinical Immunology and Immunogenicity. She has published over 15 articles in international peer-reviewed journals.

Inhaltsangabe

1. Introduction: canonical vs non-canonical autophagy 2. Overview of Canonical Autophagy 3. Overview of Non-Canonical Autophagy 4. LC3-associated phagocytosis (LAP) 5. Autophagy-dependent cell death (ADCD) 6. Therapeutic targeting of non-conventional autophagy: potential benefits and pitfalls

Rezensionen

"This is an excellent book covering molecular mechanisms underlying non-canonical autophagy and the therapeutic potential and development of autophagy modulators. There are very few books which cover the molecular mechanisms underlying non-canonical autophagy. Weighted Numerical Score: 85 - 3 Stars" --© Doody's Review Service, 2021, Omer Iqbal, reviewer, expert opinion