Nitric oxide is a highly potent regulatory molecule with great pharmaceutical potential. This handbook fills a real gap in combining the chemistry of nitric oxide releasing substances with their practical applications in biology and drug design. It covers all classes of nitric oxide donors, from organic nitrates to nitroso compounds, guanidines and metal-NO complexes. In addition to a detailed treatment of the chemistry of NO donors, numerous examples of successful diagnostic and pharmacological applications are discussed, as well as further therapeutic targets for these substances.
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"Having this information at the fingertips is a valuable resource, and this book would make an excellent addition to the personal library of anyone studying NO donors or using these compounds in their research." - Journal of Medicinal Chemistry
"This collection of review articles provides a thorough overview of the chemistry, biochemistry, and pharmacology of nitric oxide donors." - E-STREAMS
"For everyone working in the field, the book covers not only the background and established knowledge, but also new developments, in a compressed, competent, modern, concise, and nicely arranged way. For some years to come, this book will be recognized as certainly the best compendium on NO donors and - to some extent - on the physiological effects of NO." - Angewandte Chemie
"This collection of review articles provides a thorough overview of the chemistry, biochemistry, and pharmacology of nitric oxide donors." - E-STREAMS
"For everyone working in the field, the book covers not only the background and established knowledge, but also new developments, in a compressed, competent, modern, concise, and nicely arranged way. For some years to come, this book will be recognized as certainly the best compendium on NO donors and - to some extent - on the physiological effects of NO." - Angewandte Chemie