Neurobiology of Autism (eBook, ePUB)

• Format: ePub

Produktbeschreibung

This volume in the International Review of Neurobiology is a comprehensive overview of the state-of-the-art research into autism pathophysiology. Its chapters cover a wide range of etiologies, from genetics and development to environmental factors. In addition, it discusses key cell and behavioral phenotypes, including cortical and cerebellar phenotypes, as well as language and motor outputs. Finally, this volume's chapters on gene expression in the brain describe how genes may be connected to phenotypes in autism.

• Broad coverage of genetic and cellular phenotypes in autism
• Focused on basic research
• Chapters primarily written by new investigators with a fresh perspective on the biological underpinnings of autism

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 384
• Erscheinungstermin: 27. November 2013
• Englisch
• ISBN-13: 9780124199613
• Artikelnr.: 40157641

Inhaltsangabe

1. Autism Spectrum Disorder and the Cerebellum


Esther B. E. Becker and Catherine J. Stoodley




2. Contribution of Long Noncoding RNAs (lncRNAs) to Autism Spectrum Disorder Risk


Brent Wilkinson and Daniel B. Campbell




3. Identifying Essential Cell Types and Circuits in Autism Spectrum Disorders


Susan E. Maloney, Michael A. Rieger, and Joseph D. Dougherty




4. Connecting Signaling Pathways Underlying Communication to ASD Vulnerability


Stephanie Lepp, Ashley Anderson, and Genevieve Konopka




5. MET Receptor Tyrosine Kinase as an Autism Genetic Risk Factor


Yun Peng, Matt Huentleman, Christopher Smith, and Shenfeng Qiu




6. Transcriptional Dysregulation of Neocortical Circuit Assembly in ASD


Kenneth Y. Kwan




7. Motor Skill in Autism Spectrum Disorders: A Subcortical View


Leanne Chukoskie, Jeanne Townsend, and Marissa Westerfield




8. Orchestration of Neurodevelopmental Programs by RBFOX1: Implications for Autism Spectrum Disorder


Brent R. Bill, Jennifer K. Lowe, Christina T. DyBuncio and Brent L. Fogel




9. Immune Dysregulation in Autism Spectrum Disorder


Elaine Y. Hsiao




10. Autism Susceptibility Genes and the Transcriptional Landscape of the Human Brain Shingo Miyauchi and Irina Voineagu