Mechanisms and Biological Significance of Pulsatile Hormone Secretion (eBook, PDF)

Redaktion: Chadwick, Derek J.; Goode, Jamie A.

• Format: PDF

Produktbeschreibung

This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the induction of biological responses. Coverage includes the basic mechanisms involved in hormone pulsatility, the significance of pulsatility in normal and disease conditions, the relevance of circadian rhythms, changes with ageing, and detailed consideration of specific peptide hormone systems. This book includes contributions from professionals working in both basic and clinical research and reveals much new and exciting work in this area and promises new research directions.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 280
• Erscheinungstermin: 9. September 2003
• Englisch
• ISBN-13: 9780470870785
• Artikelnr.: 37299931

Autorenporträt

Derek J. Chadwick and Jamie A. Goode are editors for Mechanisms and Biological Significance of Pulsatile Hormone Secretion and other scientific titles.

Inhaltsangabe

Introduction (J. Veldhuis). Rhythmic Transcription: The Molecular Basis of
Oscillatory Melatonin Synthesis (N. Foulkes, et al.). The Frequency
Encoding of Pulsatility (A. Goldbeter, et al.). Timing-Dependent Modulation
of Insulin Mitogenic Versus Metabolic Signalling (P. De Meyts & R. Shymko).
Growth Hormone Pulse-Activated STAT5 Signalling: A Unique Regulatory
Mechanism Governing Sexual Dimorphism of Liver Gene Expression (D. Waxman).
Orderliness of Hormone Release (S. Pincus). Prediction and Significance of
the Temporal Pattern of Hormone Secretion in Disease States (G. Brabant &
K. Prank). Therapeutic Implications of Circadian Rhythms in Cancer Patients
(F. Lévi). Pathophysiology of Human Circadian Rhythms (G. Copinschi, et
al.). Nature of Altered Pulsatile Hormone Release and Neuroendocrine
Network Signalling in Human Ageing: Clinical Studies of the Somatotropic,
Gonadotropic, Corticotropic and Insulin Axes (J. Veldhuis). Pulsatile
Insulin Secretion (P. Butler). Control of Growth Hormone (GH) release by GH
Secretagogues (I. Robinson). Pulsatile Parathyroid Hormone Secretion in
Health and Disease (F. Schaefer). Significance of Pulsatility in the HPA
Axis (S. Lightman, et al.). Closing Remarks (J. Veldhuis). Indexes.

Rezensionen

"This book provides a comprehensive and excellent summary of our state of knowledge,"
(Cell Biology International, May 2001)

"This outstanding text should stimulate further research on pulsatile hormone secretion that will enhance both biomedical science and clinical treatments of hormone-related disorders"
(Trends in Endocrinology & Metabolism, August 2001)