Gynaecological Cancers (eBook, PDF)

Biology and Therapeutics
Redaktion: Kehoe, Sean

• Format: PDF

Produktbeschreibung

Gynaecological cancers are categorised as 'rare' diseases, although collectively they affect over 16,000 women each year in the UK alone. There is a lack of real understanding of these conditions compared with other malignancies, possibly owing to their relative rarity when viewed as individual diseases. The 60th RCOG Study Group brought together a range of experts to examine as many biological aspects of gynaecological cancers as possible, including both surgical and non-surgical therapies. This book presents the findings of the Study Group, with contents including: * current understanding of the biology of gynaecological cancers * translation of biology to the clinic * state of the art in imaging and therapy * current clinical trials * advances in multimodal therapy * individualised treatment.

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Produktdetails

• Verlag: Royal College of Obstetricians and Gynaecologists (RCOG)
• Erscheinungstermin: 1. Juni 2011
• Englisch
• ISBN-13: 9781107777415
• Artikelnr.: 52979365

Inhaltsangabe

Part I. Biology of Gynaecological Cancers: Our Current Understanding: 1.
Morphological sub-types of ovarian carcinoma: new developments and
pathogenesis W. Glenn McCluggage; 2. Novel treatment strategies for
targeting genetic changes in endometrial cancer Susana Banerjee; 3.
Epigenetic biomarkers in ovarian cancer Robert Brown and Janet Graham; 4.
Predictive biology of ovarian cancer Christine A. Parkinson and James D.
Brenton; Part II. The Translation of Biology to the Clinic: 5. Biology of
BRCA1 and BRCA2 genes and implications for cancer management Timothy A.
Yap, Yvette Drew and Susan Shanley; 6. Implications of homologous
recombination defectiveness in ovarian cancer Richard J. Edmondson, Asima
Mukhopadhyay, Aiste Cerbinskaite and Nicola J. Curtin; 7. The future of
PARP inhibitors in the treatment of cancer Yvette Drew, Timothy A. Yap and
Stan B. Kaye; Part III. Imaging and Therapy: State of the Art: 8. The role
of robotics and the future Tim Mould; 9. 'Ultra-radical' surgery in
advanced ovarian cancer Oliver Zivanovic and Dennis S. Chi; 10.
Antivascular therapy in gynaecological cancers Leena Mukherjee and Gordon
Rustin; 11. Oncolytic viral gene therapy in ovarian cancer Iain A. McNeish;
12. Endometrial cancer: what have the clinical trials taught us? Andrew
Clamp; 13. Targeting therapies in cancer: opportunities in ovarian cancer
Ahmed Ashour Ahmed, Stefan Knapp, Anil K. Sood and Robert C. Bast Jr; 14.
Functional imaging: from tumour biology to the clinic Nandita M. deSouza,
Evis Sala, Stavroula Kyriazi and Andrea Rockall; Part IV. What Questions
Are Being Asked by Current Clinical Trials?: 15. Current clinical trials in
ovarian cancer Christina Fotopoulou, Angus McIndoe, Jalid Sehouli and Hani
Gabra; 16. Clinical trials in cervical cancer Karen Tipples and Melanie
Powell; 17. Clinical trials in vulval cancer Tito Lopes; Part V. Consensus
Views: 18. Consensus views arising from the 60th Study Group:
Gynaecological Cancers: Biology and Therapeutics; Index.