G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part A (eBook, ePUB)

• Format: ePub

Produktbeschreibung

G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation, Part A, Volume 337 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This new release includes comprehensive sections on the classical paradigms of GCPR signaling and regulation, the family of small GTPases: Beyond heterotrimeric G proteins, GPCR endocytosis: Arrestins, arrestin-like proteins, signaling from internalized G Protein-Coupled Receptors, GPCR kinases, and more.

• Publishes only invited review articles on selected topics
• Authored by established and active cell and molecular biologists whose work is drawn from international sources
• Offers a wide range of perspectives on specific subjects

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 182
• Erscheinungstermin: 23. April 2018
• Englisch
• ISBN-13: 9780128137734
• Artikelnr.: 50474194

Autorenporträt

Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla's research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.

Inhaltsangabe

1. Classical Paradigms of GCPR signaling and regulation 2. The family of small GTPases: Beyond heterotrimeric G proteins 3. GPCR endocytosis: Arrestins, arrestin-like proteins and beyond 4. Signaling from internalized G Protein-Coupled Receptors 5. GPCR kinases: Something old, something new 6. Ubiquitination of GPCRs: Roles in endocytosis and receptor turnover 7. RAMPs: Discovery and future perspective 8. Cross-talk between GPCRs and RTKs: Novel signaling platforms 9. "Regulator of G protein signaling" protein family: Fine-tuning and emerging paradigms 10. GCPR-interacting lipids: Structural, functional and signaling implications