Fundamentals and Applications of Fourier Transform Mass Spectrometry (eBook, ePUB)

Redaktion: Schmitt-Kopplin, Philippe; Kanawati, Basem

• Format: ePub

Produktbeschreibung

Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data.

• Covers FT-ICR-MS and Orbitrap's fundamentals, enhancing researcher knowledge
• Includes details on ion sources, data processing, chemical analysis and imaging
• Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 778
• Erscheinungstermin: 11. August 2019
• Englisch
• ISBN-13: 9780128140147
• Artikelnr.: 61689223

Autorenporträt

Dr. Schmitt-Kopplin's research team performs tailored and comprehensive metabolomics in health and environment. He has a strong profile in analytical chemistry with integrated approaches combining (ultra)high resolution mass spectrometry, separation sciences, NMR-spectroscopy and bioinformatics for the description of complex molecular systems on a molecular level. His focus in the last decade was to implement ion cyclotron resonance Fourier transform mass spectrometry into applications for a rapid and robust tool for deep metabotyping and small molecules profiling. His interdisciplinary studies are related to important diseases linked to environmental factors and microbiome engineering such as in diabetes, asthma and allergies, probiotics, intestinal infections, and microbial pathogens.

Inhaltsangabe

Historical Chapters
1. Historical Developments in FTICRMS

Fundamental/Technology Chapters
2. Fundamentals of Orbitrap
3. Latest developments in FT-ICR-MS
4. Fundamentals and simulations in FT-ICR-MS
5. Advanced Fundamentals
6. Data processing & Automation in ICR-FT-MS
7. Fundamentals of 2D-FTMS
8. Ion Mobility and FTMS
9. Imaging FTMS
10. Laser Desorption Ionisation FT-ICR-MS

Applications Chapters
11. LC-MS Metabolomics in Orbitrap
12. Visualizing metabolic hypotheses on FT-ICR-MS
13. Environmental Chemistry/Organohalogens and FTMS
14. Bioactive Peptides
15. Forensic studies FTMS/Orbitrap
16. Petroleomics Orbitrap/FTMS
17. Proteomics/PTM Orbi/ICR
18. Gas Phase Ion-Molecule Reactions / Inorganics
19. Clusters Chemistry and Cold ICR-FTMS
20. Application of FTMS to the Analysis of Glycosaminoglycans
21. Foodomics in FTMS

Rezensionen

"Apart from this book that, at its time, provided a well-balanced introduction and state-of-the-art overview, there are only books containing single chapters on FT-ICR-MS or Orbitrap-MS. Overall, this book deserves a place on the bookshelves not only of academic libraries but even more so in MS laboratories using FT-based instrumentation. This review rates it at four of five stars." --Analytical and Bioanalytical Chemistry

"Basically, this monograph is well-structured and the assignment of the chapters into Sections A to C provides orientation for the reader. Generally, the authors have taken great care to provide well prepared and informative chapters each contributing to the whole package offered by this book." --Analytical and Bioanalytical Chemistry