Gary S. Firestein, Ralph C. Budd, Sherine E Gabriel, Iain B McInnes, James R. O'Dell

Firestein & Kelley's Textbook of Rheumatology - E-Book (eBook, ePUB)

Firestein & Kelley's Textbook of Rheumatology - E-Book
Redaktion: Koretzky, Gary

• Format: ePub

Produktbeschreibung

Through 10 outstanding editions, Kelley & Firestein's Textbook of Rheumatology has provided authoritative, in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. The 11th Edition of this classic text continues this tradition of excellence, while keeping you abreast of recent advances in genetics and the microbiome, new therapies such as biologics and biosimilars, and other rapid changes in the field. It provides comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, in a user-friendly, full color reference.

• Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes-including key data on therapeutic outcomes to better inform clinical decision making.
• Includes new chapters on Innate Lymphoid Cells and Natural Killer Cells, Pathogenesis of Inflammasome Mediated Diseases, Bisphosphonates, Ultrasound Evaluation of the Musculoskeletal System, and Evaluation of Monoarticular and Polyarticular Arthritis.
• Features 1,200 high-quality illustrations, including superb line art, quick-reference tables, and full-color clinical photographs.
• Shares the knowledge and expertise of internationally renowned scientists and clinicians, including new editor Dr. Gary Koretzky, specialist in immunology and rheumatology.
• Demonstrates the complete musculoskeletal exam in online videos, including abnormal findings and the arthroscopic presentation of diseased joints.

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Produktdetails

• Verlag: Elsevier HealthScience EN
• Seitenzahl: 2400
• Erscheinungstermin: 5. Juli 2020
• Englisch
• ISBN-13: 9780323639217
• Artikelnr.: 68399818

Autorenporträt

Gary Firestein, MD, is a board-certified rheumatologist who diagnoses and treats patients with autoimmune conditions as well as diseases of the joints, muscles and bones. A professor at UC San Diego School of Medicine, Dr. Firestein is distinguished for his research and serves as director of the Altman Clinical and Translational Research Institute and the senior associate vice chancellor for health sciences. Dr. Firestein's research interest focuses on the pathogenesis and treatment of rheumatoid arthritis.
Dr. Firestein is the recipient of many awards and honors, including the Arthritis Foundation's Jane Wyman Humanitarian Award in 2010 for his contributions to rheumatology; the Arthritis Foundation Lee C. Howley Sr. Prize for Arthritis Research; and the American College of Rheumatology Distinguished Investigator Award. He has been elected to the American Society for Clinical Investigation and the Association of American Physicians. He has served as an editor for the Textbook of Rheumatology for since the 7th edition (2004).

Inhaltsangabe

VOLUME I

Part 1: Structure and Function of Bone, Joints, and Connective Tissue

1. Biology of the Normal Joint, 1 Carla R. Scanzello and Steven R. Goldring

2. Synovium, 20 Douglas J. Veale and Gary S. Firestein

3. Cartilage and Chondrocytes, 34 Ali Mobasheri, Mary B. Goldring, and Richard F. Loeser

4. Biology, Physiology, and Morphology of Bone, 60 Aline Bozec, Anika Grüneboom, and Georg Schett

5. Muscle: Anatomy, Physiology, and Biochemistry, 67 Mark S. Miller, Edward P. Debold, and Michael J. Toth

6. Biomechanics, 80 Kenton R. Kaufman and KaiNan An

7. Regenerative Medicine and Tissue Engineering, 92 Frank P. Luyten, Cosimo De Bari, and Francesco Dell'Accio

8. Proteinases and Matrix Degradation, 109 Yoshifumi Itoh

Part 2: Cells Involved in Autoimmune Diseases and Inflammation

9. Dendritic Cells, 132 Mansi Saxena, Nicolas Vabret, Luciana Ribeiro Muniz, and Nina Bhardwaj

10. Mononuclear Phagocytes, 149 Deborah R. Winter, Anna Montgomery, and Harris Perlman

11. Neutrophils, 161 Binita Shah, Nathalie Burg, and Michael H. Pillinger

12. T Lymphocytes, 182 Ralph C. Budd

13. B Cells, 199 Yong-Rui Zou, Christine Grimaldi, and Betty Diamond

14. Fibroblasts and Fibroblast-like Synoviocytes, 222 Christopher D. Buckley and Andrew Filer

15. Mast Cells, 241 Peter A. Nigrovic

16. Innate Lymphoid Cells and Natural Killer Cells, 254 Michael A. Paley and Wayne M. Yokoyama

17. Platelets and Megakaryocytes, 262 Eric Boilard and Peter A. Nigrovic

Part 3: Effector Mechanisms in Autoimmunity and Inflammation

18. Principles of Signaling, 273 Abel Suarez-Fueyo, Vaishali R. Moulton, and George C. Tsokos

19. The Immunologic Repercussions of Cell Death, 286 Helen M. Beere and Douglas R. Green

20. Innate Immunity, 306 Gregoire Lauvau and Steven A. Porcelli

21. Adaptive Immunity, 320 Martha S. Jordan and Gary A. Koretzky

22. Autoimmunity and Tolerance, 337 Dwight H. Kono and Argyrios N. Theofilopoulos

23. The Microbiome in Health and Disease, 355 Rob Knight

24. Metabolic Regulation of Immunity, 368 Ruoning Wang, Tingting Wang, and Stephen Tait

25. Genetics of Rheumatic Diseases, 378 Stephen Eyre and Anne Barton

26. Epigenetics of Rheumatic Diseases, 393 Amr H. Sawalha and Matlock A. Jeffries

27. Complement System, 409 V. Michael Holers and Leendert A. Trouw

28. Prostaglandins, Leukotrienes, and Related Compounds, 420 Robert B. Zurier

29. Chemokines and Cellular Recruitment, 437 Gerard Graham

30. Angiogenesis, 445 Ursula Fearon, Zoltán Szekanecz, and Douglas J. Veale

31. Cytokines, 455 Iain B. McInnes

32. Experimental Models for Rheumatoid Arthritis, 467 Rikard Holmdahl

33. Neuronal Regulation of Pain and Inflammation, 480 Camilla I. Svensson and Linda S. Sorkin

Part 4: Broad Issues in the Approach to Rheumatic Disease

34. Clinical Research Methods in Rheumatic Disease, 495 Jeffrey R. Curtis, Yvonne M. Golightly, and Kenneth G. Saag

35. Economic Impact of Arthritis and Rheumatic Conditions, 510 Louise B. Murphy

36. Assessment of Health Outcomes, 522 Dorcas E. Beaton, Maarten Boers, Peter Tugwell, and Lara Maxwell

37. Biomarkers in Rheumatology, 536 Michael J. Townsend, Saloumeh K. Fischer, and Andrew C. Chan

38. Occupa

Rezensionen

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