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Updated and expanded, this Second Edition of Essentials of Clinical Radiation Oncology continues to provide a succinct and effective review of the most important studies in the field. Organized by disease topic and grouped by body part, each chapter employs structured sections for targeted information retrieval and retention. Chapters begin with a "Quick Hit" overview of each disease summarizing the most significant paradigms before moving into dedicated summaries on epidemiology, risk factors, anatomy, pathology, genetics, screening, clinical presentation, workup, prognostic factors, staging,…mehr
Updated and expanded, this Second Edition of Essentials of Clinical Radiation Oncology continues to provide a succinct and effective review of the most important studies in the field. Organized by disease topic and grouped by body part, each chapter employs structured sections for targeted information retrieval and retention. Chapters begin with a "Quick Hit" overview of each disease summarizing the most significant paradigms before moving into dedicated summaries on epidemiology, risk factors, anatomy, pathology, genetics, screening, clinical presentation, workup, prognostic factors, staging, treatment paradigm, and medical management. An evidence-based question-and-answer section concludes each chapter, which pairs commonly encountered clinical questions with answers connecting historical context and pertinent clinical studies to better inform decision-making and treatment planning.
Providing the latest treatment paradigms and guidelines, this comprehensive second edition now outlines the evidence and must-know considerations for using radiation therapy with immunotherapy, the strategies for metastasis-directed therapy for oligometastatic disease, and much more. Written for the practicing radiation oncologist, related practitioner, and radiation oncology resident entering the field, this "one-stop" resource is the go-to reference for everyday practice.
Key Features:
Structured sections offer high-yield information for targeted review
Cites need-to-know clinical studies and treatment guidelines in evidence-based question-and-answer format
Each chapter has been reviewed and updated to include the most recent and relevant studies
New chapters on spine tumors, thyroid cancer, sinonasal tumors, cholangiocarcinoma, renal cell carcinoma, multiple myeloma and plasmacytoma, miscellaneous pediatric tumors, and treatment of oligometastatic disease from underlying cancers
Designed for quick reference with comprehensive tables on treatment options and patient selection, workup, and prognostic factors by disease site
Purchase includes digital access for use on most mobile devices or computers
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Contributors Preface 1. I. CENTRAL NERVOUS SYSTEM 2. 1. Glioblastoma by Aditya Juloori, Jennifer S. Yu, and Samuel T. Chao 3. 2. Anaplastic Gliomas by Shireen Parsai, Martin C. Tom, and Samuel T. Chao 4. 3. Low Grade Gliomas by Martin C. Tom and Erin S. Murphy 5. 4. Meningioma by Martin C. Tom, David J. Schwartz, and Abigail L. Stockham 6. 5. Primary Central Nervous System Lymphoma by Ian W. Winter, Samuel T. Chao, and Erin S. Murphy 7. 6. Pituitary Adenoma by Zachary Mayo and John H. Suh 8. 7. Trigeminal Neuralgia by Bindu V. Manyam, Vamsi Varra, and Samuel T. Chao 9. 8. Vestibular Schwannoma by Winston Vuong, Jeffrey A. Kittel, and John H. Suh 10. 9. Uveal Melanoma by Martin C. Tom, Guarav Marwaha, John H. Suh, and Arun D. Singh 11. 10. Spine Tumors by Sarah S. Kilic, Ehsan H. Balagamwala, and Samuel T. Chao 12. II. HEAD AND NECK 13. 11. Oropharynx Cancer by Shireen Parsai, Aditya Juloori, Nikhil P. Joshi, and Shlomo A. Koyfman 14. 12. Oral Cavity Cancer by Kailin Yang, Bindu V. Manyam, and Neil M. Woody 15. 23. Nasopharyngeal Cancer by Christopher W. Fleming, Shireen Parsai, and Nikhil P. Joshi 16. 14. Laryngeal Cancer by Aditya Juloori, Shauna R. Campbell, and Shlomo A. Koyfman 17. 15. Salivary Gland Tumors by Sarah S. Kilic, Martin C. Tom, Shlomo A. Koyfman, and Nikhil P. Joshi 18. 16. Carcinoma of Unknown Primary of the Head and Neck (HCNUP) by Monika E. Shukla and Jeffrey A. Kittel 19. 17. Postoperative Radiation for Head and Neck Cancer by Timothy D. Smile and Carryn M. Anderson 20. 18. Thyroid Cancer by James R. Broughman and Nikhil P. Joshi 21. 19. Sinonasal Tumors by Timothy D. Smile and Neil M. Woody 22. III. SKIN 23. 20. Non-Melanoma Skin Cancer by Ian W. Winter, Neil M. Woody, and Shlomo A. Koyfman 24. 21. Malignant Cutaneous Melanoma by Sarah S. Kilic, Aditya Juloori, and Nikhil P. Joshi 25. 22. Mycosis Fungoides by Vamsi Varra, Matthew C. Ward, and Gregory M. M. Videtic 26. IV. BREAST 27. 23. Early-Stage Breast Cancer by Kailin Yang, Rahul D. Tendulkar, and Chirag Shah 28. 24. Locally Advanced Breast Cancer by Christopher W. Fleming, Yvonne D. Pham, and Rahul D. Tendulkar 29. 25. Ductal Carcinoma In Situ by Timothy D. Smile, Rahul D. Tendulkar, and Chirag Shah 30. 26. Recurrent Breast Cancer by Ian W. Winter, Camille A. Berriochoa, and Chirag Shah 31. V. THORACIC 32. 27. Early-Stage Non-Small-Cell Lung Cancer by Sarah S. Kilic, by Guarav Marwaha, Kevin L. Stephans, and Gregory M. M. Videtic 33. 28. Stage III Non-Small-Cell Lung Cancer by Aditya Juloori, Matthew C. Ward, and Gregory M. M. Videtic 34. 29. Small-Cell Lung Cancer by Camille A. Berriochoa and Gregory M. M. Videtic 35. 30. Mesothelioma by Sarah M. C. Sittenfeld, Bindu V. Manyam, and Gregory M. M. Videtic 36. 31. Thymoma by Christopher W. Fleming, Jonathan M. Sharrett, and Gregory M. M. Videtic 37. VI. GASTROINTENTINAL 38. 32. Esophageal Cancer by Camille A. Berriochoa and Gregory M. M. Videtic 39. 33. Gastric Cancer by Bindu V. Manyam, Kevin L. Stephans, and Gregory M. M. Videtic 40. 34. Hepatocellular Carcinoma by Shauna R. Campbell, Neil M. Woody, and Kevin L. Stephans 41. 35. Pancreatic Adenocarcinoma by James R. Broughman and Ehsan H. Balagamwala 42. 36. Rectal Cancer by Ian W. Winter, Ehsan H. Balagamwala, and Sudha R. Amarnath 43. 37. Anal Cancer by Kristine Bauer-Nilson, Aditya Juloori, and Sudha R. Amarnath 44. 38. Cholangiocarcinoma by Christopher W. Fleming, Shauna R. Campbell, and Kevin L. Stephans 45. VII. GENITOURINARY 46. 39. Low-Risk Prostate Cancer by Timothy D. Smile and Rahul D. Tendulkar 47. 40. Intermediate- and High-Risk Prostate Cancer by Rahul D. Tendulkar, Bindu V. Manyam, and Omar Y. Mian 48. 41. Post-Prostatectomy Radiation Therapy James R. Broughman, Camille A. Berriochoa, and Rahul D. Tendulkar 49. 42. Bladder Cancer by Winston Vuong, Omar Y. Mian, and Rahul D. Tendulkar 50. 43. Testicular Cancer by Zachary Mayo, Ehsan H. Balagamwala, and Rahul D. Tendulkar 51. 44. Penile Cancer by Rahul D. Tendulkar, Rupesh Kotecha, and Omar Y. Mian 52. 45. Urethral Cancer by Rahul D. Tendulkar, Rupesh Kotecha, and Omar Y. Mian 53. 46. Renal Cell Carcinoma by Sarah M. C. Sittenfeld and Rahul D. Tendulkar 54. VIII. GYNECOLOGIC 55. 47. Cervical Cancer by Sudha Amarnath, Monica E. Shukla, and Sheen Cherian 56. 48. Uterine Cancers by Shireen Parsai, Sarah M. C. Sittenfeld, Michael Weller, and Sudha R. Amarnath 57. 49. Vulvar Cancer by Ahmed Halima and Sudha R. Amarnath 58. 50. Vaginal Cancer by Camille A. Berriochoa and Sudha R. Amarnath 59. IX. HEMATOLOGIC 60. 51. Adult Hodgkin's Lymphoma by Matthew C. Ward and Sheen Cherian 61. 52. Aggressive Non-Hodgkin's Lymphoma by James R. Broughman, Matthew C. Ward, and Chirag Shah 62. 53. Indolent Non-Hodgkin's Lymphoma by Christopher W. Fleming, Aryavarta M. S. Kumar, and Matthew C. Ward 63. 54. Multiple Myeloma and Plasmacytoma by Kailin Yang and Sheen Cherian 64. X. SARCOMA 65. 55. Soft Tissue Sarcoma by Shauna R. Campbell, Jonathan Sharrett, Jacob G. Scott, and Chirag Shah 66. XI. PEDIATRIC 67. 56. Medulloblastoma by Timothy D. Smile, Camille A. Berriochoa, and Erin S. Murphy 68. 57. Ependymoma by Matthew C. Ward, John H. Suh, and Erin S. Murphy 69. 58. Brainstem Glioma by Sarah M. C. Sittenfeld, Jason W. D. Hearn, and John H. Suh 70. 59. Craniopharyngioma by Martin C. Tom, Timothy D. Smile, and Erin S. Murphy 71. 60. Rhabdomyosarcoma by Shauna R. Campbell, Samuel T. Chao, and Erin S. Murphy 72. 61. Neuroblastoma by Charles Marc Leyrer and Erin S. Murphy 73. 62. Wilms Tumor by James R. Broughman and Erin S. Murphy 74. 63. Ewing's Sarcoma by Kailin Yang, Ehsan H. Balagamwala, and Erin S. Murphy 75. 64. Pediatric Hodgkin's Lymphoma by Sarah M. C. Sittenfeld and Erin S. Murphy 76. 65. Miscellaneous Pediatric Tumors by Shauna R. Campbell and Erin S. Murphy 77. XII. METASTATES AND PALLIATIVE RADIOTHERAPY 78. 66. Brain Metastases by Shauna R. Campbell, Martin C. Tom, and John H. Suh 79. 67. Bone Metastasis by Ehsan H. Balagamwala, Samuel T. Chao, and Andrew Vassil 80. 68. Malignant Spinal Cord Compression by Camille A. Berriochoa and Bindu V. Manyam 81. 69. Superior Vena Cava Syndrome by Kailin Yang and Gregory M. M. Videtic 82. 70. Palliative Radiotherapy by Matthew C. Ward and Justin J. Juliano 83. 71. Oligometastatic Disease by Ian W. Winter, Ehsan H. Balagamwala, and Martin C. Tom 84. XIII. BENIGN DISEASES 85. 72. Radiation Therapy for Benign Diseases by Ahmed Halima and Chirag Shah Abbreviations List
Contributors Preface 1. I. CENTRAL NERVOUS SYSTEM 2. 1. Glioblastoma by Aditya Juloori, Jennifer S. Yu, and Samuel T. Chao 3. 2. Anaplastic Gliomas by Shireen Parsai, Martin C. Tom, and Samuel T. Chao 4. 3. Low Grade Gliomas by Martin C. Tom and Erin S. Murphy 5. 4. Meningioma by Martin C. Tom, David J. Schwartz, and Abigail L. Stockham 6. 5. Primary Central Nervous System Lymphoma by Ian W. Winter, Samuel T. Chao, and Erin S. Murphy 7. 6. Pituitary Adenoma by Zachary Mayo and John H. Suh 8. 7. Trigeminal Neuralgia by Bindu V. Manyam, Vamsi Varra, and Samuel T. Chao 9. 8. Vestibular Schwannoma by Winston Vuong, Jeffrey A. Kittel, and John H. Suh 10. 9. Uveal Melanoma by Martin C. Tom, Guarav Marwaha, John H. Suh, and Arun D. Singh 11. 10. Spine Tumors by Sarah S. Kilic, Ehsan H. Balagamwala, and Samuel T. Chao 12. II. HEAD AND NECK 13. 11. Oropharynx Cancer by Shireen Parsai, Aditya Juloori, Nikhil P. Joshi, and Shlomo A. Koyfman 14. 12. Oral Cavity Cancer by Kailin Yang, Bindu V. Manyam, and Neil M. Woody 15. 23. Nasopharyngeal Cancer by Christopher W. Fleming, Shireen Parsai, and Nikhil P. Joshi 16. 14. Laryngeal Cancer by Aditya Juloori, Shauna R. Campbell, and Shlomo A. Koyfman 17. 15. Salivary Gland Tumors by Sarah S. Kilic, Martin C. Tom, Shlomo A. Koyfman, and Nikhil P. Joshi 18. 16. Carcinoma of Unknown Primary of the Head and Neck (HCNUP) by Monika E. Shukla and Jeffrey A. Kittel 19. 17. Postoperative Radiation for Head and Neck Cancer by Timothy D. Smile and Carryn M. Anderson 20. 18. Thyroid Cancer by James R. Broughman and Nikhil P. Joshi 21. 19. Sinonasal Tumors by Timothy D. Smile and Neil M. Woody 22. III. SKIN 23. 20. Non-Melanoma Skin Cancer by Ian W. Winter, Neil M. Woody, and Shlomo A. Koyfman 24. 21. Malignant Cutaneous Melanoma by Sarah S. Kilic, Aditya Juloori, and Nikhil P. Joshi 25. 22. Mycosis Fungoides by Vamsi Varra, Matthew C. Ward, and Gregory M. M. Videtic 26. IV. BREAST 27. 23. Early-Stage Breast Cancer by Kailin Yang, Rahul D. Tendulkar, and Chirag Shah 28. 24. Locally Advanced Breast Cancer by Christopher W. Fleming, Yvonne D. Pham, and Rahul D. Tendulkar 29. 25. Ductal Carcinoma In Situ by Timothy D. Smile, Rahul D. Tendulkar, and Chirag Shah 30. 26. Recurrent Breast Cancer by Ian W. Winter, Camille A. Berriochoa, and Chirag Shah 31. V. THORACIC 32. 27. Early-Stage Non-Small-Cell Lung Cancer by Sarah S. Kilic, by Guarav Marwaha, Kevin L. Stephans, and Gregory M. M. Videtic 33. 28. Stage III Non-Small-Cell Lung Cancer by Aditya Juloori, Matthew C. Ward, and Gregory M. M. Videtic 34. 29. Small-Cell Lung Cancer by Camille A. Berriochoa and Gregory M. M. Videtic 35. 30. Mesothelioma by Sarah M. C. Sittenfeld, Bindu V. Manyam, and Gregory M. M. Videtic 36. 31. Thymoma by Christopher W. Fleming, Jonathan M. Sharrett, and Gregory M. M. Videtic 37. VI. GASTROINTENTINAL 38. 32. Esophageal Cancer by Camille A. Berriochoa and Gregory M. M. Videtic 39. 33. Gastric Cancer by Bindu V. Manyam, Kevin L. Stephans, and Gregory M. M. Videtic 40. 34. Hepatocellular Carcinoma by Shauna R. Campbell, Neil M. Woody, and Kevin L. Stephans 41. 35. Pancreatic Adenocarcinoma by James R. Broughman and Ehsan H. Balagamwala 42. 36. Rectal Cancer by Ian W. Winter, Ehsan H. Balagamwala, and Sudha R. Amarnath 43. 37. Anal Cancer by Kristine Bauer-Nilson, Aditya Juloori, and Sudha R. Amarnath 44. 38. Cholangiocarcinoma by Christopher W. Fleming, Shauna R. Campbell, and Kevin L. Stephans 45. VII. GENITOURINARY 46. 39. Low-Risk Prostate Cancer by Timothy D. Smile and Rahul D. Tendulkar 47. 40. Intermediate- and High-Risk Prostate Cancer by Rahul D. Tendulkar, Bindu V. Manyam, and Omar Y. Mian 48. 41. Post-Prostatectomy Radiation Therapy James R. Broughman, Camille A. Berriochoa, and Rahul D. Tendulkar 49. 42. Bladder Cancer by Winston Vuong, Omar Y. Mian, and Rahul D. Tendulkar 50. 43. Testicular Cancer by Zachary Mayo, Ehsan H. Balagamwala, and Rahul D. Tendulkar 51. 44. Penile Cancer by Rahul D. Tendulkar, Rupesh Kotecha, and Omar Y. Mian 52. 45. Urethral Cancer by Rahul D. Tendulkar, Rupesh Kotecha, and Omar Y. Mian 53. 46. Renal Cell Carcinoma by Sarah M. C. Sittenfeld and Rahul D. Tendulkar 54. VIII. GYNECOLOGIC 55. 47. Cervical Cancer by Sudha Amarnath, Monica E. Shukla, and Sheen Cherian 56. 48. Uterine Cancers by Shireen Parsai, Sarah M. C. Sittenfeld, Michael Weller, and Sudha R. Amarnath 57. 49. Vulvar Cancer by Ahmed Halima and Sudha R. Amarnath 58. 50. Vaginal Cancer by Camille A. Berriochoa and Sudha R. Amarnath 59. IX. HEMATOLOGIC 60. 51. Adult Hodgkin's Lymphoma by Matthew C. Ward and Sheen Cherian 61. 52. Aggressive Non-Hodgkin's Lymphoma by James R. Broughman, Matthew C. Ward, and Chirag Shah 62. 53. Indolent Non-Hodgkin's Lymphoma by Christopher W. Fleming, Aryavarta M. S. Kumar, and Matthew C. Ward 63. 54. Multiple Myeloma and Plasmacytoma by Kailin Yang and Sheen Cherian 64. X. SARCOMA 65. 55. Soft Tissue Sarcoma by Shauna R. Campbell, Jonathan Sharrett, Jacob G. Scott, and Chirag Shah 66. XI. PEDIATRIC 67. 56. Medulloblastoma by Timothy D. Smile, Camille A. Berriochoa, and Erin S. Murphy 68. 57. Ependymoma by Matthew C. Ward, John H. Suh, and Erin S. Murphy 69. 58. Brainstem Glioma by Sarah M. C. Sittenfeld, Jason W. D. Hearn, and John H. Suh 70. 59. Craniopharyngioma by Martin C. Tom, Timothy D. Smile, and Erin S. Murphy 71. 60. Rhabdomyosarcoma by Shauna R. Campbell, Samuel T. Chao, and Erin S. Murphy 72. 61. Neuroblastoma by Charles Marc Leyrer and Erin S. Murphy 73. 62. Wilms Tumor by James R. Broughman and Erin S. Murphy 74. 63. Ewing's Sarcoma by Kailin Yang, Ehsan H. Balagamwala, and Erin S. Murphy 75. 64. Pediatric Hodgkin's Lymphoma by Sarah M. C. Sittenfeld and Erin S. Murphy 76. 65. Miscellaneous Pediatric Tumors by Shauna R. Campbell and Erin S. Murphy 77. XII. METASTATES AND PALLIATIVE RADIOTHERAPY 78. 66. Brain Metastases by Shauna R. Campbell, Martin C. Tom, and John H. Suh 79. 67. Bone Metastasis by Ehsan H. Balagamwala, Samuel T. Chao, and Andrew Vassil 80. 68. Malignant Spinal Cord Compression by Camille A. Berriochoa and Bindu V. Manyam 81. 69. Superior Vena Cava Syndrome by Kailin Yang and Gregory M. M. Videtic 82. 70. Palliative Radiotherapy by Matthew C. Ward and Justin J. Juliano 83. 71. Oligometastatic Disease by Ian W. Winter, Ehsan H. Balagamwala, and Martin C. Tom 84. XIII. BENIGN DISEASES 85. 72. Radiation Therapy for Benign Diseases by Ahmed Halima and Chirag Shah Abbreviations List
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