Dynamic Force Spectroscopy and Biomolecular Recognition (eBook, PDF)

Redaktion: Bizzarri, Anna Rita; Cannistraro, Salvatore

• Format: PDF

Produktbeschreibung

Molecular recognition, also known as biorecognition, is the heart of all biological interactions. Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies a

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 270
• Erscheinungstermin: 25. Januar 2012
• Englisch
• ISBN-13: 9781439862384
• Artikelnr.: 38302241

Autorenporträt

Anna Rita Bizzarri received her degree in Physics in 1987 from the University of Rome. She obtained the Ph.D. in Biophysics in 1992 from SISSA in Trieste. After postdoctoral fellowships in Perugia and Mainz she joined the Science Faculty at Tuscia University, Italy, as research assistant. In 2000, she became Associate Professor of Physics and in 2006 she got the position of full Professor. Her scientific interests include spectroscopic investigations and MD simulations of electron transfer metalloproteins. More recently, she has focused on single-molecule level detection by surface enhanced Raman spectroscopy and scanning probe microscopies for both fundamental and applicative aims. Salvatore Cannistraro obtained his degree in Physics in 1972 from Pisa University. He received his Ph.D. in Biophysics at Liegi University,Belgium. In 1977, he became reader of Biophysics at Calabria University. He moved to Perugia University in 1981 as Associate Professor of Molecular Physics. Since 1991, he has been a full professor of Physics, Biophysics, and Nanoscience at Tuscia University, leading the Biophysics and Nanoscience Centre. His scientific interests include optical, magnetic, neutron spectroscopies and modelling of amorphous and biological systems. More recently, he is focusing his activity on the application of AFM, STM, and Raman SERS to single biomolecule detection and nanobiomedicine.

Inhaltsangabe

Biomolecular Recognition: The Current Challenge. Atomic Force Microscopy
and Spectroscopy. Theoretical Models in Force Spectroscopy. Immobilization
and Interaction Strategies in DFS of Biomolecular Partners. Biomolecular
Recognition: Analysis of DFS Data. Biological Applications of Dynamical
Force Spectroscopy. Conclusions and Perspective. Index.