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This new volume of Advances in Pharmacology presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years which has revealed specific physiological and pharmacological functions of individual GABA A receptor subtypes, providing novel opportunities for drug development. Contributions from the best authors in the field | An essential resource for pharmacologists, immunologists, and biochemists
This new volume of Advances in Pharmacology presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development.
Contributions from the best authors in the field
An essential resource for pharmacologists, immunologists, and biochemists
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Inhaltsangabe
1. The Legacy of the Benzodiazepine Receptor: From Flumazenil to Enhancing Cognition in Down Syndrome and Social Interaction in Autism Hanns Möhler 2. Behavioral Functions of GABAA Receptor Subtypes - the Zurich Experience Florence Crestani and Uwe Rudolph 3. Allosteric Modulation of GABAA Receptors via Multiple Drug Binding Sites Werner Sieghart 4. Regulation of GABAARs by Phosphorylation Yasuko Nakamura, Laura M. Darnieder, Tarek Z. Deeb and Stephen J. Moss 5. Endozepines Zoya Farzampour, Richard J. Reimer and John Huguenard 6. Inhibitory Neurosteroids and the GABAA Receptor Sandra Seljeset, Duncan Laverty and Trevor G Smart 7. Interactions of Flavonoids with Ionotropic GABAA Receptors Jane R Hanrahan, Mary Chebib and Graham A R Johnston 8. GABAA Receptor Partial Agonists and Antagonists: Structure, Binding Mode, and Pharmacology Jacob Krall, Thomas Balle, Niels Krogsgaard-Larsen, Troels E. Sørensen, Povl Krogsgaard-Larsen, Uffe Kristiansen and Bente Frølund 9. Closing the Gap between the Molecular and Systemic Actions of Anesthetic Agents Bernd Antkowiak
1. The Legacy of the Benzodiazepine Receptor: From Flumazenil to Enhancing Cognition in Down Syndrome and Social Interaction in Autism Hanns Möhler 2. Behavioral Functions of GABAA Receptor Subtypes - the Zurich Experience Florence Crestani and Uwe Rudolph 3. Allosteric Modulation of GABAA Receptors via Multiple Drug Binding Sites Werner Sieghart 4. Regulation of GABAARs by Phosphorylation Yasuko Nakamura, Laura M. Darnieder, Tarek Z. Deeb and Stephen J. Moss 5. Endozepines Zoya Farzampour, Richard J. Reimer and John Huguenard 6. Inhibitory Neurosteroids and the GABAA Receptor Sandra Seljeset, Duncan Laverty and Trevor G Smart 7. Interactions of Flavonoids with Ionotropic GABAA Receptors Jane R Hanrahan, Mary Chebib and Graham A R Johnston 8. GABAA Receptor Partial Agonists and Antagonists: Structure, Binding Mode, and Pharmacology Jacob Krall, Thomas Balle, Niels Krogsgaard-Larsen, Troels E. Sørensen, Povl Krogsgaard-Larsen, Uffe Kristiansen and Bente Frølund 9. Closing the Gap between the Molecular and Systemic Actions of Anesthetic Agents Bernd Antkowiak
Rezensionen
Praise for the Series: "...recommended not only to pharmacologists but also to all those in related disciplines" --Nature
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