Developability of Biotherapeutics (eBook, PDF)
Computational Approaches
Redaktion: Kumar, Sandeep; Kumar Singh, Satish
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Developability of Biotherapeutics (eBook, PDF)
Computational Approaches
Redaktion: Kumar, Sandeep; Kumar Singh, Satish
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This reference describes applications of computational and molecular modeling techniques toward more efficient and affordable biopharmaceutical drug development at the pre-clinical stages that could positively impact clinical outcomes. With a primary focus on the developability of monoclonal antibody candidates, it addresses many contributions that computation can make towards biopharmaceutical drug development in general. It is a rich source of information on current principles and practices and provides a starting point for finding innovative applications of computation in biotherapeutics.
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- Größe: 12.38MB
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- Produktdetails
- Verlag: Taylor & Francis
- Seitenzahl: 315
- Erscheinungstermin: 18. November 2015
- Englisch
- ISBN-13: 9781482246155
- Artikelnr.: 44195096
- Verlag: Taylor & Francis
- Seitenzahl: 315
- Erscheinungstermin: 18. November 2015
- Englisch
- ISBN-13: 9781482246155
- Artikelnr.: 44195096
Applications of Computation in Biologic Drug Development. Computational
Methods in the Optimization of Biologic Modalities. Understanding,
Predicting, and Mitigating the Impact of Posttranslational Physiochemical
Modifications, Including Aggregation, on the Stability of Biopharmaceutical
Drug Products. Preclinical Immunogenicity Risk Assessment of
Biotherapeutics. Application of Mechanistic Pharmacokinetic-Pharmacodynamic
Modeling toward the Development of Biologics. Challenges in
High-Concentration Biopharmaceutical Drug Delivery: A Modeling Perspective.
DEVELOPABILITY PRACTICES IN THE BIOPHARMACEUTICAL INDUSTRY. Best Practices
in Assessment of Developability of Biopharmaceutical Candidates. Best
Practices in Developability Assessments of Therapeutic Protein Candidates
in the Biopharmaceutical Industry. Best Practices in Assessing the
Developability of Biopharmaceutical Candidates. Developability Assessment
Workflows to De-Risk Biopharmaceutical Development.
Applications of Computation in Biologic Drug Development. Computational
Methods in the Optimization of Biologic Modalities. Understanding,
Predicting, and Mitigating the Impact of Posttranslational Physiochemical
Modifications, Including Aggregation, on the Stability of Biopharmaceutical
Drug Products. Preclinical Immunogenicity Risk Assessment of
Biotherapeutics. Application of Mechanistic Pharmacokinetic-Pharmacodynamic
Modeling toward the Development of Biologics. Challenges in
High-Concentration Biopharmaceutical Drug Delivery: A Modeling Perspective.
DEVELOPABILITY PRACTICES IN THE BIOPHARMACEUTICAL INDUSTRY. Best Practices
in Assessment of Developability of Biopharmaceutical Candidates. Best
Practices in Developability Assessments of Therapeutic Protein Candidates
in the Biopharmaceutical Industry. Best Practices in Assessing the
Developability of Biopharmaceutical Candidates. Developability Assessment
Workflows to De-Risk Biopharmaceutical Development.