Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection (eBook, ePUB)

Revolutionary Strategies to Combat Pandemics
Redaktion: Parihar, Arpana; Gohel, Hardik; Kaushik, Ajeet Kumar; Kumar, Ashok; Khan, Raju

• Format: ePub

Produktbeschreibung

Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection: Revolutionary Strategies to Combat Pandemics compiles information about various computational bioinformatic approaches that can help combat viral infection. The book includes working knowledge of various molecular docking and molecular dynamic simulation approaches that have been exploited for drug repurposing and drug designing purpose. In addition, it sheds light on reverse vaccinomics and immunoinformatic approaches for vaccine designing against SARS-CoV2 infection.

This book is an essential resource for researchers, bioinformaticians, computational biologists, computational chemists and pharmaceutical companies who are working on the development of effective and specific therapeutic interventions and point-of-care diagnostic devices using various computational approaches.

• Covers computational based approaches for designing and repurposing drugs
• Discusses immunoinformatic and reverse vaccinomic approaches for effective vaccine design
• Categorizes information about artificial intelligence-based drug screening and diagnostic tools

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 618
• Erscheinungstermin: 13. Juli 2022
• Englisch
• ISBN-13: 9780323998000
• Artikelnr.: 64314400

Inhaltsangabe

1. Overview of coronavirus pandemic
2. Epidemiology and pathogenesis of novel coronavirus (SARS-COV-2)
3. The Global impact of pandemic on world economy and public health
response
4. Genomic, proteomic and metabolomic profiling of SARS-CoV2
5. Current Challenges in development of therapeutic and diagnostic
application for SARS-CoV2 detection
6. Available drugs for treatment of SARS-CoV2 and their side effects
7. Genomic and proteomic targets for development of drugs to combat
pandemic
8. The classical approaches for drug design and development
9. Natural products as a therapy to combat against SARS-COV2 virus
infection
10. Support of computational methods to design and develop therapies
11. Computational methods for optimizing drugs and delivery methods to
manage COVID-19 pandemic
12. Pharmacophore mapping and modelling approaches for drug development
13. Quantitative structure activity relationship based computational
approaches
14. Molecular docking and molecular dynamic simulation approaches for drug
development and repurposing
15. Computational approaches for drug repositioning and repurposing to
combat SARS-CoV2 infection
16. Network biology and system biology based computational approaches for
drug repositioning
17. Databases, drug bank and virtual screening platforms for therapeutic
development
18. Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET)
assessment of drugs using computational tools
19. Immuno-informatics and reverse vaccinomic approaches for effective
vaccine design
20. Artificial Intelligence based drug screening and repurposing tools and
their application in present scenario
21. Machine learning and deep learning-based AI tools for development of
diagnostic tools
22. Role and development of artificial intelligence-based smartphone apps
for point-of-care coronavirus infection diagnostics
23. Present therapeutic and diagnostic approaches for SARS-CoV-2 infection
24. Clinically available/ under trial drugs and vaccines for treatment of
SARS-CoV-2
25. Present and Future challenges in therapeutic designing using
computational approaches
26. AI enabled IoT in covid-19 detection and monitoring entire digital
healthcare
27. Remote monitoring and management in vitro diagnostic (IVD) devices as
fixed assets
28. Predict potential downtime of any IVD solutions deployed in a
customer's clinical setting
29. Recommendation systems for the best IVD solution for a customer's needs
30. Digital healthcare data visualization and analytics for better
decision-making