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Based on the bestselling Handbook of Phase I/II Clinical Drug Trials, this newly named, completely revised and expanded volume details how recent advances and increasing demands for safety and efficacy have changed the process by which drugs are developed and approved. It examines critical considerations for trials conducted during each phase of clinical development. It also explores early pre-clinical evaluations of pharmacological activity and safety. Ten sections examining clinical assessment are organized according to anatomical targets (e.g. CNS, liver), functions (e.g. metabolic, chemotherapeutic) with another section covering vaccines, biotechnology-derived therapeutics, and plant-based medicines.
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