Chronic Obstructive Pulmonary Disease (eBook, PDF)

Redaktion: Stockley, Robert A.; Celli, Bartolome; Rabe, Klaus; Rennard, Stephen I

• Format: PDF

Produktbeschreibung

The only international clinical textbook for COPD - one of the top 5 causes of death and disability worldwide * The only COPD textbook to include the latest national and international guidelines and the newer therapeutic agents in COPD treatment * International team of contributors covers all aspects of COPD - from physiology and epidemiology to diagnosis and treatment Everything the busy physician needs to understand, diagnose and treat the COPD patient: * Structure and physiology of the respiratory system * Clinical considerations and allied conditions * Therapy (including current and developing treatments) * Diagnostic tests used in daily practice

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 912
• Erscheinungstermin: 8. Mai 2008
• Englisch
• ISBN-13: 9780470755280
• Artikelnr.: 38186240

Autorenporträt

Professor Robert Stockley is the Head of Department at the Queen Elizabeth Hospital in Birmingham. He is a respiratory physician working in the field of chronic obstructive pulmonary disease. Professor Stephen Rennard is Larson Professor of Medicine in the Pulmonary and Critical Care Medicine Section of the Department of Internal Medicine at the University of Nebraska Medical Center in Omaha, Nebraska. He is the North American Editor for Respiratory Medicine and Associate Editor for COPD for the European Respiratory Journal. Professor Klaus Rabe is Professor of Pulmonary Medicine and Chairman for the Department of Pneumology in the University of Leiden. He has been active in various fields of respiratory medicine in Europe and was the first European Associate Editor of the American Journal of Respiratory and Critical Care Medicine. He is co-Chief Editor of the European Respiratory Journal. Dr Bart Celli is Professor of Medicine at Tufts University in Boston and Chief of the Division of Pulmonary and Critical Care Medicine at the St Elizabeth's Medical Center at Tufts University School of Medicine. He is the author of more than 120 publications on COPD and is the co-editor of Baum's Textbook of Pulmonary Diseases and Hodgkin's Textbook in Pulmonary Rehabilitation.

Inhaltsangabe

Section 1: Physiology.

1 Structure-Function Relationships: the Pathophysiology ofAirflow Obstruction.

2 The Physiology of Breathlessness.

3 The Physiology of Muscle.

4 Exercise Limitations and Cardiopulmonary Exercise Testing inCOPD.

5 Clinical Assessment of Control of Breathing.

6 Physiology and Pathobiology of the LungCirculation.

7 Sleep in Patients with COPD.

8 The Physiology of Cough.

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9 The Physiology of Gas Exchange.

.

Section 2: COPD and Allied Conditions.

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10 The Natural History of COPD.

11 Cystic Fibrosis.

12 Bronchiectasis and COPD.

13 Obliterative Bronchiolitis.

14 Asthma.

15 COPD: Clinical Presentation and Evaluation.

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16 Monitoring and Outcomes.

Section 3: Host Defences and Inflammation.

17 Mucociliary Clearance.

18 Mucosal Immunity.

19 COPD and Pulmonary Surfactant.

20 The Macrophage and its Role in the Pathogenesis of COPD.

21 Eosinophils and COPD.

22 Airway Epithelial Defence, Repair and Regeneration.

23 The Role of the Neutrophil in the Pathogenesis of COPD.

24 Lymphocytes.

25 Cytokines.

26 Leukotrienes in COPD: The Unexploited Potential.

27 Cigarette Smoking, Emphysema and Lung Endothelium.

28 Mesenchymal Cells of the Lung.

Section 4: Pathogenesis.

29 Lung Development.

30 Animal Models.

31 Proteinases and COPD.

32 Oxidants.

33 Cigarette Smoke-Induced Disease.

34 COPD and Air Pollution.

35 Viruses in COPD.

36 Bacteria.

37 Genetic Factors.

38 alpha1-Antitrypsin Deficiency.

39 Body Weight and Systemic Effects.

40 Lung Connective Tissue.

Section 5: Clinical Considerations and Complications.

41 Aerosols and Delivery Systems.

42 Gastro-oesophageal Reflux.

43 Upper Airway Diseases.

44 Acute Pulmonary Embolism.

45 COPD and Lung Cancer.

46 Infection Management and Airflow Obstruction.

47 Mechanical Ventilation for Exacerbation of COPD.

48 Comorbidity.

Section 6: Current and Future Treatment.

49 Primary Care.

50 Pulmonary Rehabilitation.

51 Social Support.

52 Long-Term Invasive Mechanical Ventilation.

53 Smoking Cessation.

54 Oxygen Therapy in COPD.

55 Surgical Therapy for COPD.

56 Anticholinergics in COPD.

57 beta2-Agonists.

58 Corticosteroids.

59 Phosphodiesterase 4 Inhibitors in the Treatment of COPD.

60 Antibiotic Therapy in Patients with COPD.

61 Antioxidants.

62 Mucolytics for COPD.

63 End-of-Life and Palliative Care for Patients withCOPD.

64 Economic Burden of COPD.

65 Pharmacoepidemiology of COPD.

66 Social and Behavioural Impact of COPD - ResearchOpportunities.

67 Guidelines.

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Section 7: Pharmacotherapy: Developing Therapies.

68 Protease Inhibitors.

69 Retinoids.

70 Chemokines in COPD.

Index

Rezensionen

"Appropriate to the intense proliferation of research andpublications in the last few decades for this major health problem,the editors of Chronic Obstructive Pulmonary Disease haveproduced a comprehensive textbook that spans the basic and clinicalscience of COPD. This substantial tome includes 912 pages, 243illustrations, and 70 chapters authored by an international cadreof contributors...

The succinct writing style, judicious use of complementaryillustrations, and well-focused references achieve the desiredbreadth without compromising sufficient depth orreadability...

Section 3 focuses on cellular physiology and inflammation. Thissection exemplifies the strength of this textbook, digesting alarge body of developing science into comprehensible synopses ofthe disease processes that form the basis for therapeuticopportunities...

In summary, the editors and authors of Chronic ObstructivePulmonary Disease have achieved their goal by creating acurrent textbook covering many facets of this complex disorder. Inparallel with the field of COPD, the textbook has its strength inthe scientific underpinnings of airway and lung physiology andadvances in the understanding of cellular and physiologicalderangements." - Richard A. Mularski (MD, MSHS, MRC), JAMA,September 2007

"The strength of the book lies in the more than 100authors...recognized worldwide. Most of the chapters areexcellent reviews and are carefully referenced."
New England Journal of Medicine

"...In summary, the editors and authors of ChronicObstructive Pulmonary Disease have achieved their goal bycreating a current textbook covering many facets of this complexdisorder. In parallel with the field of COPD, the textbook has itsstrength in the scientific underpinnings of airway and lungphysiology and advances in the understanding of cellular andphysiological derangements"Richard A. Mularski for JohnL. Zeller, MD, PhD, Fishbein Fellow Books and Media Reviews SectionEditor, JAMA

"This book does an outstanding job of outlining the majoraspects of COPD. Topics are organized logically and each chapterhas ample references...highlighting important concepts."
Doodys Reviews