Kurt Faber

Biotransformations in Organic Chemistry (eBook, PDF)

A Textbook

• Format: PDF

Produktbeschreibung

The use of biocatalysts, employed either as isolated enzymes or whole cells, offers a remarkable arsenal of highly selective transformations for modern preparative organic chemistry. During the last decade, this methodology has now generally been accepted as a complementary method to the already existing tools. This first textbook on biocatalysis provides a basis for undergraduate and graduate courses in biocatalysis, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts - principles of stereoselective transformations, kinetics, enzyme nomenclature and handling - the different types of reactions are explained according to the "reaction principle". The 5th edition...

From www.biochemist.org, 2/2005, Dr. Chris Hamilton, Queens University Belfast

"... To summarize, the book is comprehensive, well structured and easy to read either cover-to-cover or by just dipping into a particular topic of interest. It is a combination of a general introduction to the theoretical principles of synthetic biotransformations, an outline of the practicalities which need to be considered and a compact, yet comprehensive, review of discoveries and developments which have driven this field towards maturity over the past twenty years. I found it to be an informative and enjoyable read and would recommend it as a central textbook both for synthetic chemists already involved in biotransformations as well as a good starting point for those who have yet to take the plunge."

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Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 454
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783642185373
• Artikelnr.: 53133338

Autorenporträt

Kurt Faber obtained his PhD in synthetic organic chemistry at the University of Graz in 1982. He then became a postdoctoral fellow at the Memorial University of Newfoundland. After moving to TU Graz as an University assistant, Faber was a visiting senior scientist at the University of Tokyo and at Exeter University. In 1990 he received his habilitation in Organic Chemistry at the Institute of Organic Chemistry, University of Technology Graz where he was appointed to Associate Professor in 1997, in the following year he moved to the Institute of Organic Chemistry at the University of Graz where he holds a full professorship. Faber's career was supplemented by becoming a visiting senior scientist at the University of Trondheim, Stockholm University, the University of Minnesota and the ESPCI in Paris.

Inhaltsangabe

Introduction.- Common Prejudices Against Enzymes.- Advantages and Disadvantages of Biocatalysts. Enzyme Properties and Nomenclature.- Biocatalytic Applications: Hydrolytic Reactions.- Reduction Reactions.- Oxidation Reactions.- Formation of Carbon-Carbon Bonds.- Addition and Elimination Reactions.- Transfer Reactions.- Halogenation and Dehalogenation Reactions.- Special Techniques: Enzymes in Organic Solvents.- Cascade Reactions.- Immobilization.- Artificial and Modified Enzymes.- State of the Art and Outlook.- Appendix: Basic Rules for Handling Biocatalysts.- Abbreviations.- Suppliers of Enzymes.- Commonly Used Enzyme Preparations.- Major Culture Collections.- Pathogenic Bacteria and Fungi.- Index.