Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging (eBook, ePUB)

Volume 5 - Role in Human Diseases
Redaktion: Hayat, M. A.

• Format: ePub

Produktbeschreibung

Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst inciting researchers to explore their potentially important connections.

Volume 5 comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders. In spite of the increasing importance of autophagy in the various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases remains poorly understood.

This book is an asset to newcomers as a concise overview of the diverse disease implications of autophagy, while serving as an excellent reference for more experienced scientists and clinicians looking to update their knowledge.

Volumes in the Series

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 338
• Erscheinungstermin: 26. September 2014
• Englisch
• ISBN-13: 9780128010549
• Artikelnr.: 41659589

Autorenporträt

Dr. Hayat has published extensively in the fields of microscopy, cytology, immunohistochemistry, immunocytochemistry, and antigen retrieval methods. He is Distinguished Professor, Department of Biological Sciences, Kean University, Union, New Jersey, USA.

Inhaltsangabe

I. General Applications

Chapter 1. Introduction; M. A. Hayat

II. Role of Autophagy in Cancer

Chapter 2. Molecular Crosstalk between the Autophagy and Apoptotic Networks in Cancer; James Driscoll

Chapter 3. Inhibition of ERBB Receptors and Autophagy in Cancer Therapy; Ronit Pinkas-Kramarski

Chapter 4. Ginsenoside F2 Initiates an Autophagic Progression in Breast Cancer Stem Cells; Somi Kim Cho

Chapter 5. Role of Autophagy in Cancer Therapy; Ricardo Gargini

Chapter 6. Autophagy in Human Brain Cancer. Therapeutic Implications; Clelia Miracco

Chapter 7. Blockage of Lysosomal Degradation is Detrimental to Cancer Cells' Survival: Role of Autophagy Activation; Jessica L. Schwartz-Roberts

Chapter 8. Induction of Protective Autophagy in Cancer cells by an NAE Inhibitor MLN4924; Yi Sun

Chapter 9. Effect of Autophagy on Chemotherapy-induced Apoptosis and Growth Inhibition; Shanshan Zhang

Chapter 10. Autophagy Upregulation Reduces Doxorubicin-induced Cardiotoxicity; Balindiwe J.N. Sishi

III. Role of Autophagy in Cardiovascular, Metabolic, and Neurodegenerative Diseases

Chapter 11. Autophagy in Critical Illness; Rajesh K. Aneja

Chapter 12. Autophagy in the Onset of Atrial Fibrillation; Rodrigo Troncoso

Chapter 13. Role of Autophagy in Atherogenesis; Peggy Robinet

Chapter 14. Regulation of Autophagy in Insulin Resistance and Type 2 Diabetes; Monika Cahova

Chapter 15. Pancreatic Beta Cell Autophagy and Islet Transplantation; Subbiah Pugazhenthi

Chapter 16. Autophagy Guards against Immunosuppression and Renal Ischemia-Reperfusion Injury in Renal Transplantation; Yoshitaka Isaka

Chapter 17. When the Good Turns Bad: Challenges in the Targeting of Autophagy in Neurodegenerative Diseases; Melissa Nassif

Chapter 18. The a-Tubulin Deacetylase HDAC6 in Aggresome formation and autophagy: Implications for neurodegeneration; Christiane Richter-Landsberg