Lester M. Crawford, Don A. Franco

Animal Drugs and Human Health (eBook, PDF)

• Format: PDF

Produktbeschreibung

The presence of drug and chemical residues in food products from animal sources is both a public health problem and a consumer concern. This is the first book to examine and analyze this problem in a scientific, non-partisan way.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 234
• Erscheinungstermin: 26. Juli 2020
• Englisch
• ISBN-13: 9781000125153
• Artikelnr.: 59826503

Autorenporträt

EXECUTIVE DIRECTOR ASSOCIATION OF AMERICAN VE1ERINARY MEDICAL COLLEGES WASHINGlON, D.C. DIRECTOR, SOENTIFIC SERVICES, NATIONAL RENDERERS ASSOCIATION and DIRECTOR, SCIENTIFIC AFFAIRS, ANIMAL PROTEIN PRODUCERS INDUSTRY ALEXANDRIA, VA.

Inhaltsangabe

Foreword
Acknowledgements
1. THE PUBLIC HEALTH PERSPECTIVE /LESTER M. CRAWFORD, D.V.M., Ph.D. and DON A. FRANCO, DVM., M.P.H., Dipl. A.CVP.M.
l . l Introduction
1.2 The Public Health Implications Associated with Antibiotics, Pesticides and Hormones
1.3 Summary
I .4 References
2. PHARMACOLOGICAL PRINCIPLES OF THE DISPOSITION OF DRUGS AND OTHER XENOBIOTICS /JUDI WEISSINGER, DVM., Ph.D. and LESTER M. CRAWFORD, DVM., Ph.D.
2.1 Introduction
2. 2 Absorption
2. 3 Route of Administration
2 .4 Distribution
2.5 Biotransformation
2.6 Excretion
2. 7 Bioavailability
2. 8 Residue Considerations
2. 9 References
3. PRINCIPLES A ND IMPLEMENTATION OF RESIDUE PROGR AMS IN ME AT AND POULTRY INSPECTION /RONALD E. ENGEL, D.V.M., Ph.D.
3.1 Introduction
3.2 Establishment of MRL:s (Tolerance or Action Levels)
3.3 Analytical Methods
3.4 Laboratory Quality Assurance
3.5 Criteria for Compound Evaluation and Selection
3.6 Statistical Design Criteria
3. 7 Education and Residue Avoidance
3.8 Enforcement Programs
3. 9 Conclusion
3. 10 References
4. METHODS OF DETECTION /RICHARD ELLIS, Ph.D.
4. I Introduction
4.2 Neeo for Regulatory Analytical Methods
4.3 Attributes of Regulatory Analytical Methods
4.4 Categories of Analytical Methods for Regulatory Programs
4.5 Method Development and Validation Procedures for Regulatory Methods
4.6 Quality Assurance and Quality Control
4. 7 Examples of Regulatory Control Methods
4.8 Trends and Emerging Technologies
4. 9 International Considerations
4.10 Summary
4. 1 1 References
5. ANTIBIOTIC RESIDUES AND THE PUBLIC HEALTH /ROBERT C. WILSON, D.VM., Ph.D.
5. 1 Introduction
5.2 Incidence of Antibiotic Residues
5.3 Tests for Residues
5 .4 Sources of Residues
5.5 Public Health Significance of Antibiotic Drug Residues
5.6 Summary
5.7 References
6. CAUSES, DETECTION, AND CORRECTION OF SULFONAMIDE RESIDUES IN SWINE /RICHARD F. BEVILL, D.V.M., Ph.D.
6.1 Introduction
6.2 Causes of Sulfonamide Residues
6.3 Characteristics of Feed Handling or Water Systems Which Predispose to Carryover of Sulfamethazine from Medicated to Nonmedicated Rations
6.4 Detection of Sulfonamide Residues
6.5 Methods to Prevent or Reduce the Occurrence of Sulfa Residues
6.6 Summary
6.7 References
7. HORMONES /DON A. FRANCO, D.V.M., M.P.H , Dipl. ACVPM and CATHERINE E. ADAMS, Ph.D., R.D.
7. I Introduction
7.2 Classification
7.3 The Use, Action and Effects of Anabolic Agents in Food
Producing Animals
7.4 Public Health Impact /International Debate
7.5 Summary
7 .6 References
8. MISCELLANEOUS GROWTH PROMOTANTS /JUDI WEISSINGER, DVM , Ph.D.
8.1 Introduction
8.2 Pharmacology
8.3 Pharmacokinetics
8.4 Toxicity
8.5 Veterinary Medical Use (Utilization)
8.6 Resistance
8.7 Residues in Edible Animal Tissues
8.8 Analyses and Assays
8.9 Summary
8.10 References
9. PARASITICIOES /T. B. BARRAGRY, Ph.D
9.1 Introduction
9.2 Benzimidazolcs
9.3 Salicylanilides and Substituted Phenols
9.4 lmidothiazoles
Levamisole
9.5 Organophosphates
9.6 Tetra Hydropyrimidines
9.7 Avermectins
9.8 Summary
9.9 References
10. PESTICIDE RESIDUES IN FOODS OF ANIMAL ORIGIN /W. D. BLACK, D.V.M., M.Sc., Ph.D.
10.1 Introduction
10.2 Importance of Pesticides to Man
10.3 Characteristics of the Major Insecticide Groups
10.4 Usage oflnsecticides in Livestock
10. 5 Causes of Residues
10.6 Regional Differences in Pesticide Residues
10. 7 International Response
10.8 ADI's and MRL's
10. 9 Residues and Food Intake Determinations
10.10 National Response
10. 11 Residue Testing Programs
10.12 Impact of Residue Control Programs
10.13 Implications for Human Safety
10.14 Cancer Risk Assessment
10.15 Significance of Residues in Food
10.16 References
11. HERBICIDES /JOSEPH V. KITZMAN, D.V.M., Ph.D.
11.1 Introduction
11.2 Herbicides
What Are They?
1 1.3 EPA Toxicology Requirements for Herbicide Registration
1 1.4 Monitoring Herbicide Residue in Foods
11.5 References
12. DECON TAMIN ATION OF LIVESTOCK /WILLIAM T. BUCK. D.V.MM.S.
12.1 Introduction
12.2 General Considerations
12.3 Potential Sources
12 .4 Field Cases 2
12.5 Summary
12.6 References.