Advances in Protein Molecular and Structural Biology Methods (eBook, ePUB)
Redaktion: Tripathi, Timir; Dubey, Vikash Kumar
Advances in Protein Molecular and Structural Biology Methods (eBook, ePUB)
Redaktion: Tripathi, Timir; Dubey, Vikash Kumar
- Format: ePub
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Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also…mehr
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It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application.
- Presents a thorough overview of the latest and emerging methods and technologies for protein study
- Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy
- Includes computational and machine learning methods
- Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins
Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.
- Produktdetails
- Verlag: Elsevier Science & Techn.
- Seitenzahl: 714
- Erscheinungstermin: 14. Januar 2022
- Englisch
- ISBN-13: 9780323902656
- Artikelnr.: 63298825
- Verlag: Elsevier Science & Techn.
- Seitenzahl: 714
- Erscheinungstermin: 14. Januar 2022
- Englisch
- ISBN-13: 9780323902656
- Artikelnr.: 63298825
yeast
insect
and mammalian cells 1. Strategies to Improve the Expression and Solubility of Recombinant Proteins in Bacteria Niharika Nag
Heena Khan
and Timir Tripathi 2. Advances in Heterologous Protein Expression Strategies in Yeast and Insect Systems Meenakshi Singh
Smita Gupta
Arun Kumar Rawat
Sudhir Kumar Singh 3. Methods for Transient Expression and Purification of Monoclonal Antibodies in Mammalian Cells Suchitra Kamle
Dawei Li
Chun Geun Lee
Jack A. Elias 4. Methods for Recombinant Production and Purification of Intrinsically Disordered Proteins Steffen P. Graether Section 2: Biophysical techniques including
NMR
X-ray crystallography
cryo-EM
etc. 5. Methods to Determine the Oligomeric Structure of Proteins Purna Bahadur Chetri
Heena Khan
and Timir Tripathi 6. Multimodal Methods to Study Protein Aggregation and Fibrillation Maria Georgina Herrera
Marco Giampà
Nicolo Tonali and Veronica Isabel Dodero 7. Experimental Methods to Study the Thermodynamics of Protein-Protein Interactions Santanu Sasidharan
Niharika Nag
Timir Tripathi
and Prakash Saudagar 8. Experimental Methods to Study the Kinetics of Protein-Protein Interactions Abhay Narayan Singh
Kristijan Ramadan
Shalini Singh 9. Computational Techniques to Study Protein-Protein Interactions Khattab Al-Khafaji
Tugba Taskin-Tok 10. Experimental Methods to Study Protein-Nucleic Acid Interactions Roberto Giambruno
Jakob Rupert
and Elsa Zacco 11. Advanced Computational Tools for Quantitative Analysis of Protein-nucleic acid Interfaces Sunandan Mukherjee and Chandran Nithin 12. Experimental Techniques to Study Protein Dynamics and Conformations Akshita Gupta
Anamika Singh
Nabeel Ahmad
Tej P. Singh
Sujata Sharma
Pradeep Sharma 13. Computational Techniques to Study Protein Dynamics and Conformations Laura Orellana
Anil Mhashal
and Agusti Emperador 14. Application of Circular Dichroism Spectroscopy in Studying Protein Folding
Stability
and Interaction Md. Anzarul Haque
Punit Kaur
Asimul Islam
and Md. Imtaiyaz Hassan 15. Studying Protein Folding Dynamics using Single Molecule Fluorescence Methods Narattam Mandal
Krishnananda Chattopadhyay
Achinta Sannigrahi 16. Advances in Liquid-state NMR Spectroscopy to Study the Structure
Function
and Dynamics of Biomacromolecules Priyanka Aggarwal
Pooja Kumari and Neel Sarovar Bhavesh 17. In-Cell NMR Spectroscopy: A Tool for Cellular Structure Biology Vijay Kumar 18. Current Trends in Membrane Protein Crystallography Koomity V. Nageswar
Mansi Sharma
Dipak N. Patil
Santoshi Nayak
Anwesha Roy
Appu K. Singh 19. Advances in Sample Preparation and Data Processing for Single-particle Cryo-Electron Microscopy Anshul Assaiya
Suparna Bhar and Janesh Kumar 20. Advanced Mass Spectrometry-Based Approaches for Molecular-Structural Biologists Joanna Bons
Jacob Rose
Amy O'Broin
and Birgit Schilling 21. Developments
Advancements
and Contributions of Mass Spectrometry in Omics Technologies Saravanan Kumar 22. Role of Structural Biology Methods in Drug Discovery Fouzia Nasim and Insaf Ahmed Qureshi Section 3: Computational methods including MD simulation
coupling MD and deep machine learning
etc 23. Prediction
Validation
and Analysis of Protein Structures: A Beginner's Guide Santanu Sasidharan and Prakash Saudagar 24. Advances in Structure-Based Virtual Screening for Drug Discovery Olujide O. Olubiyi
Suman Samantray and Alexander-Maurice Illig 25. Methods and Applications of Machine Learning in Structure-Based Drug Discovery Madhumathi Sanjeevi
Prajna N Hebbar
Natarajan Aiswarya
Rashmi S.
Chandrasekar Narayanan Rahul
Ajitha Mohan
Jeyaraman Jeyakanthan and Kanagaraj Sekar 26. Molecular Dynamics Simulations: Principles
Methods
and Applications in Protein Conformational Dynamics Aditya K. Padhi
Matej Janezic
Kam Y. J. Zhang 27. Applications of Molecular Dynamics Simulations in Drug Discovery Xubo Lin 28. Envisaging the Conformational Space of Proteins by Coupling Machine Learning and Molecular Dynamics Murali Aarthy
Sanjeev Kumar Singh 29. Immunoinformatics and Reverse Vaccinology Methods to Design Peptide-based Vaccines Vinita Sharma
Satyendra Singh
Tadi Sai Ratnakar
Vijay Kumar Prajapati Section 4: Tools and techniques to study IDPs 30. Computational Methods to Study Intrinsically Disordered Proteins Prateek Kumar
Aparna Bhardwaj
Vladimir N. Uversky
Timir Tripathi
and Rajanish Giri 31. Experimental Methods to Study Intrinsically Disordered Proteins Niharika Nag
Purna B Chetri
Vladimir N. Uversky
Rajanish Giri
and Timir Tripathi 32. Analysis of Structure and Dynamics of Intrinsically Disordered Regions in Proteins using Solution NMR Methods Nikita V Saibo
Snigdha Maiti
Bidisha Acharya
and Soumya De 33. Methods to Study the Effect of Solution Variables on the Conformational Dynamics of IDPs Hakan Alici
Orkun Hasekioglu
Vladimir N. Uversky
and Orkid Coskuner-Weber 34. Molecular Simulations to Study IDP-IDP Interactions and Their Complexes Kota Kasahara Section 5: Protein interaction networks
signaling
engineering
and function
etc. 35. Exploring Large-Scale Protein Function using Systematic Mutant Analysis Amrita Arpita Padhy
Subhashree Sahoo
Shivani Kumari
Varsha Kumari
Parul Mishra 36. Approaches and Methods to Study Cell Signaling: Linguistics of Cellular Communication Siddharth Neog and Vishal Trivedi 37. Methods to Study Systems Biology of Signaling Networks: A Case Study of NSCLC Nikhil H. Samarth and Shailza Singh 38. Advancements in the Analysis of Protein Post-Translational Modifications Sandip Mukherjee
Ritesh Kumar
Arianne L. Theiss
and K. Venuprasad 39. Protein Engineering: Methods and Applications Saurabh Bansal and Bishwajit Kundu 40. Designer 3D-DNA Nanodevices: Structures
Functions and Cellular Applications Kahkashan Bansal
Anjali Rajwar
and Dhiraj Bhatia
yeast
insect
and mammalian cells 1. Strategies to Improve the Expression and Solubility of Recombinant Proteins in Bacteria Niharika Nag
Heena Khan
and Timir Tripathi 2. Advances in Heterologous Protein Expression Strategies in Yeast and Insect Systems Meenakshi Singh
Smita Gupta
Arun Kumar Rawat
Sudhir Kumar Singh 3. Methods for Transient Expression and Purification of Monoclonal Antibodies in Mammalian Cells Suchitra Kamle
Dawei Li
Chun Geun Lee
Jack A. Elias 4. Methods for Recombinant Production and Purification of Intrinsically Disordered Proteins Steffen P. Graether Section 2: Biophysical techniques including
NMR
X-ray crystallography
cryo-EM
etc. 5. Methods to Determine the Oligomeric Structure of Proteins Purna Bahadur Chetri
Heena Khan
and Timir Tripathi 6. Multimodal Methods to Study Protein Aggregation and Fibrillation Maria Georgina Herrera
Marco Giampà
Nicolo Tonali and Veronica Isabel Dodero 7. Experimental Methods to Study the Thermodynamics of Protein-Protein Interactions Santanu Sasidharan
Niharika Nag
Timir Tripathi
and Prakash Saudagar 8. Experimental Methods to Study the Kinetics of Protein-Protein Interactions Abhay Narayan Singh
Kristijan Ramadan
Shalini Singh 9. Computational Techniques to Study Protein-Protein Interactions Khattab Al-Khafaji
Tugba Taskin-Tok 10. Experimental Methods to Study Protein-Nucleic Acid Interactions Roberto Giambruno
Jakob Rupert
and Elsa Zacco 11. Advanced Computational Tools for Quantitative Analysis of Protein-nucleic acid Interfaces Sunandan Mukherjee and Chandran Nithin 12. Experimental Techniques to Study Protein Dynamics and Conformations Akshita Gupta
Anamika Singh
Nabeel Ahmad
Tej P. Singh
Sujata Sharma
Pradeep Sharma 13. Computational Techniques to Study Protein Dynamics and Conformations Laura Orellana
Anil Mhashal
and Agusti Emperador 14. Application of Circular Dichroism Spectroscopy in Studying Protein Folding
Stability
and Interaction Md. Anzarul Haque
Punit Kaur
Asimul Islam
and Md. Imtaiyaz Hassan 15. Studying Protein Folding Dynamics using Single Molecule Fluorescence Methods Narattam Mandal
Krishnananda Chattopadhyay
Achinta Sannigrahi 16. Advances in Liquid-state NMR Spectroscopy to Study the Structure
Function
and Dynamics of Biomacromolecules Priyanka Aggarwal
Pooja Kumari and Neel Sarovar Bhavesh 17. In-Cell NMR Spectroscopy: A Tool for Cellular Structure Biology Vijay Kumar 18. Current Trends in Membrane Protein Crystallography Koomity V. Nageswar
Mansi Sharma
Dipak N. Patil
Santoshi Nayak
Anwesha Roy
Appu K. Singh 19. Advances in Sample Preparation and Data Processing for Single-particle Cryo-Electron Microscopy Anshul Assaiya
Suparna Bhar and Janesh Kumar 20. Advanced Mass Spectrometry-Based Approaches for Molecular-Structural Biologists Joanna Bons
Jacob Rose
Amy O'Broin
and Birgit Schilling 21. Developments
Advancements
and Contributions of Mass Spectrometry in Omics Technologies Saravanan Kumar 22. Role of Structural Biology Methods in Drug Discovery Fouzia Nasim and Insaf Ahmed Qureshi Section 3: Computational methods including MD simulation
coupling MD and deep machine learning
etc 23. Prediction
Validation
and Analysis of Protein Structures: A Beginner's Guide Santanu Sasidharan and Prakash Saudagar 24. Advances in Structure-Based Virtual Screening for Drug Discovery Olujide O. Olubiyi
Suman Samantray and Alexander-Maurice Illig 25. Methods and Applications of Machine Learning in Structure-Based Drug Discovery Madhumathi Sanjeevi
Prajna N Hebbar
Natarajan Aiswarya
Rashmi S.
Chandrasekar Narayanan Rahul
Ajitha Mohan
Jeyaraman Jeyakanthan and Kanagaraj Sekar 26. Molecular Dynamics Simulations: Principles
Methods
and Applications in Protein Conformational Dynamics Aditya K. Padhi
Matej Janezic
Kam Y. J. Zhang 27. Applications of Molecular Dynamics Simulations in Drug Discovery Xubo Lin 28. Envisaging the Conformational Space of Proteins by Coupling Machine Learning and Molecular Dynamics Murali Aarthy
Sanjeev Kumar Singh 29. Immunoinformatics and Reverse Vaccinology Methods to Design Peptide-based Vaccines Vinita Sharma
Satyendra Singh
Tadi Sai Ratnakar
Vijay Kumar Prajapati Section 4: Tools and techniques to study IDPs 30. Computational Methods to Study Intrinsically Disordered Proteins Prateek Kumar
Aparna Bhardwaj
Vladimir N. Uversky
Timir Tripathi
and Rajanish Giri 31. Experimental Methods to Study Intrinsically Disordered Proteins Niharika Nag
Purna B Chetri
Vladimir N. Uversky
Rajanish Giri
and Timir Tripathi 32. Analysis of Structure and Dynamics of Intrinsically Disordered Regions in Proteins using Solution NMR Methods Nikita V Saibo
Snigdha Maiti
Bidisha Acharya
and Soumya De 33. Methods to Study the Effect of Solution Variables on the Conformational Dynamics of IDPs Hakan Alici
Orkun Hasekioglu
Vladimir N. Uversky
and Orkid Coskuner-Weber 34. Molecular Simulations to Study IDP-IDP Interactions and Their Complexes Kota Kasahara Section 5: Protein interaction networks
signaling
engineering
and function
etc. 35. Exploring Large-Scale Protein Function using Systematic Mutant Analysis Amrita Arpita Padhy
Subhashree Sahoo
Shivani Kumari
Varsha Kumari
Parul Mishra 36. Approaches and Methods to Study Cell Signaling: Linguistics of Cellular Communication Siddharth Neog and Vishal Trivedi 37. Methods to Study Systems Biology of Signaling Networks: A Case Study of NSCLC Nikhil H. Samarth and Shailza Singh 38. Advancements in the Analysis of Protein Post-Translational Modifications Sandip Mukherjee
Ritesh Kumar
Arianne L. Theiss
and K. Venuprasad 39. Protein Engineering: Methods and Applications Saurabh Bansal and Bishwajit Kundu 40. Designer 3D-DNA Nanodevices: Structures
Functions and Cellular Applications Kahkashan Bansal
Anjali Rajwar
and Dhiraj Bhatia