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Female infertility affects millions of couples worldwide and is estimated to account for one-third of all cases of infertility. Recently natural products extracted from medical plants are very important in the field of alternative medicine. Glycosides, flavonoids and polyphenols are components of natural molecules have several health benefits such as anti-inflammatory, anti-oxidants, and have many ameliorative roles against male and female reproductiv system intractable disorders. Objective of this study was to the compound of the plant extracts blend which is rich with glycosides, flavonoids and polyphenols was named as Woman Fort. The safety as well as the efficacy of some medical plants extracts on the fertility of the female mice was investigated using Woman Fort. The safety of Woman Fort was evaluated using some mice and the levels of the follicle stimulating hormone in the serum of the treated animals with Woman Fort was evaluated using biochemical tests. Also, the effects of the Woman Fort on the histological parameters of the treated ovary and uterus were evaluated using histological analysis.