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This issue of Physical Medicine and Rehabiltiation Clinics, guest edited by Drs. Karen Barr and Ileana Michelle Howard, will cover several key aspects of Value-Added Electrodiagnostics. At the invitation of series Consulting Editor Dr. Santos Martinez, the editors put together a comprehensive issue discussing topics including: Targeting interventions for fall risk reduction; Detecting toxic myopathies as medication side effect; Predicting response from interventional spine procedures; Planning interventions to treat plexopathies; Minimizing risk of cancer therapeutics; Predicting Recovery from Peripheral Nerve Trauma; Detecting complications of metabolic syndrome and diabetes; Steering peripheral neuropathy work-up; Elucidating the cause of pelvic pain; and Guiding treatment for foot pain, among others.