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This book is the bibliographic synthesis on the vaccine from its creation to the present day containing the type of vaccine, the immunological basis of vaccination and the vaccination schedule in a simplified way that is easy to read and remember.Vaccines remain one of the pillars of modern medicine. They are often credited with much of the increase in life expectancy over the past hundred years and, along with serotherapy, represent one of the foundations of the medical revolution.The discovery of vaccines initiated one of the most effective public health policy interventions, both at the individual and collective levels, marked by the eradication of smallpox, almost 100 years after the discovery of the vaccine.After more than a century of research, vaccines are increasingly useful and developed countries are not achieving sufficient vaccination coverage of their populations. Faced with this situation and the rise of infectious diseases and epidemic and pandemic risks, how can we organize and prepare ourselves?