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This book offers expanded review of radiologic kidney anatomy , pathology and characteristic imaging of renal parenchymal diseases. It offers a review of role of ultrasound and Computed tomography guided percutaneous biopsy in patients with renal parenchymal diseases and discusses the indications , technique and possible complications. This book presents cases approached by imaging guided biopsy and discusses the results that were obtained. Research made under supervision of : Prof. Atef teama, Prof. Kamal Okasha and Ass.Prof. Sameh Khodair.