Type 2 DM management with combination therapy
Management of type 2 diabetes mellitus with insulin monotherapy, versus Combinations Therapy
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Abstract Introduction A meta analysis was conducted to evaluate the efficacy and safety profile of, insulin with oral hypoglycaemic agents, versus insulin monotherapy, in type2 diabetes patient s management. Search strategy The following databases were searched: The Cochrane Library, Medline, Embase, Pub Med, High wire Press and Science Direct. Selection criteria Randomised controlled trials (RCTs of any design) with a minimum follow-up period two months, Over 18 year old men and women were recruited with type 2 diabetes mellitus as defined by the world health Organization (Alberti 1998), part...
Abstract Introduction A meta analysis was conducted to evaluate the efficacy and safety profile of, insulin with oral hypoglycaemic agents, versus insulin monotherapy, in type2 diabetes patient s management. Search strategy The following databases were searched: The Cochrane Library, Medline, Embase, Pub Med, High wire Press and Science Direct. Selection criteria Randomised controlled trials (RCTs of any design) with a minimum follow-up period two months, Over 18 year old men and women were recruited with type 2 diabetes mellitus as defined by the world health Organization (Alberti 1998), participants were not controlled on their current oral antidiabetic agents, mean that Hba1c 7% or a fasting plasma glucose 7 mmol/l. Conclusion Insulin with oral hypoglycaemic agents gives good glycaemic control as well as prevents weight gain and less hypoglycaemia than insulin monotherapy.
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