In this remarkable volume, Dr. Jay A. Goldstein clearly presents both the theoretical and the practical aspects of this revolutionary approach to treating CFS and other conditions that have often been termed psychosomatic. Dr. Goldstein will show you how he achieves results for patients with CFS and a variety of other syndromes in days, rather than months or years. From the most basic questions--"What is neurosomatic medicine?" and "How can treatments sometimes work so rapidly?"--to specific technical concerns--"What is receptor profiling, and how does it indicate the type of receptor…mehr
In this remarkable volume, Dr. Jay A. Goldstein clearly presents both the theoretical and the practical aspects of this revolutionary approach to treating CFS and other conditions that have often been termed psychosomatic. Dr. Goldstein will show you how he achieves results for patients with CFS and a variety of other syndromes in days, rather than months or years. From the most basic questions--"What is neurosomatic medicine?" and "How can treatments sometimes work so rapidly?"--to specific technical concerns--"What is receptor profiling, and how does it indicate the type of receptor dysregulation in an individual patient?"--Tuning the Brain: Principles and Practice of Neurosomatic Medicine provides the answers in a clear and cogent manner. You'll learn which abnormalities in brain function produce neurosomatic disorders and how an understanding of these abnormalities can help you provide effective treatment.
* Foreword * Preface * Abbreviations * Part I: Inventing Neurosomatic Medicine: Rewards and Satisfactions versus Problems and Pitfalls * Chapter 1. The Education of a Neurosomaticist * Chapter 2. The Office Practice of Neurosomatic Medicine * Bankruptcy Despite a Three-Month Waiting List * Solving the Problems and Avoiding the Pitfalls * Taking Care of Business * Chapter 3. Lawyers and Litigation * Sample Pathophysiology of Posttraumatic Fibromyalgia * Mene, Mene, Tekel, Upharsin * Chapter 4. Treatment Case Examples * Instantaneous Neural Network Reconfiguration by Pharmacologic Modulation of Afferent Cranial Nerve Input * The Pathophysiology of CFS and Related Neurosomatic Disorders * Thyroid Function in Neurosomatic Disorders: Stimulation of Trigeminal Nerve Activity with Thyrotropin-Releasing Hormone (TRH) * Chapter 5. Case Reports * My So-Called Illness: Is It Real or All in My Head? * One-Second Epiphanies * My Most Unusual Case * Bug-of-the-Month Club * Chapter 6. Married to a Doctor Who Is Married to His Practice * Part II: Society for Neuroscience Conference Proceedings * Chapter 7. This Is . . . Los Angeles * Chapter 8. Neurosomatic Pearls * Eldritch Lore About Neurosomatic Therapy * Chapter 9. Neurosomatic Neuroscience * Part III: Pathophysiology and Treatment * Chapter 10. Treatment of Neurosomatic Disorders * Abecarnil and Acamprosate * Stimulants * The Corticostriatal-Thalamocortical (CSTC) Circuit in Reverse * Corticotropin-Releasing Hormone (CRH) and Hypocortisolism * Agmatine * Cholinesterase Inhibitors * Ascorbate (Vitamin C) * Amantadine * Adenosine * Baclofen * Gamma-Aminobutyric Acid (GABA) * Adenosine Triphosphate (ATP) * Lorazepam Nasal Spray * Antibiotics * Endothelin (ET) * Respiratory Rhythm Regulation in Fibromyalgia Syndrome * pH and Panic Disorder * Buspirone/BuSpar * Thalamic Reticular Nucleus * The Attentional Network * Clonidine * Catecholamines * Norepinephrine, Dopamine, Salience, and Attention * Dopamine and Reward * Effexor (Venlafaxine) * Synaptic Plasticity and Long-Term Potentiation in Neurosomatic Disorders * The Postreceptor Phosphorylation Cascade * The Treatment of Attentional Disorders * Instantaneous Neural Network Reconfiguration * Other Aspects of Synaptic Plasticity * Hormonal Modulation in Neurosomatic Medicine * Modulating the N-Methyl-D-Aspartate (NMDA) Receptor * Atypical Messengers * Synaptic Fatigue * Glutamate Receptors, Subunits, and Synaptic Scaling * Neurotrophic Factors * Metabotropic Glutamate Receptors * Conclusion * Chapter 11. Modulating Glutamatergic Neurotransmission * Ketamine * Pharmacologic Modulation of Sensory Integration via the Trigeminal Nerve * Electroconvulsive Therapy (ECT) * Kinases and Phosphatases * The Nicotinic Cholinergic Receptor * Long-Term Potentiation and Depression * Mitogen-Activated Protein Kinases (MAPKs) * Gabapentin * Zolpidem * Lamotrigine * Pentazocine (Talwin) * Oxytocin * Opioids * Oxytocin, Hypothalamic Function, and Circadian Rhythms * Other Effects of Oxytocin * Modafinil (Provigil) * Ventrolateral Preoptic Nucleus (VLPO) * Lidocaine * Gonadotropin-Releasing Hormone (GnRH) and Dysregulation of Circadian Rhythms * Pyrrolidines * Fatigue * Sleep * Conclusion * Conclusion. Closing the Circuit: The Role of the Nucleus Accumbens in Neurosomatic Disorders * Appendix * Diagnostic Criteria from the DSM-IV-TR * Treatment Algorithm * Medication List: Present and Near-Future Treatment Options for Neurosomatic Disorders * CFS Symptom Checklist * References * Index
* Foreword * Preface * Abbreviations * Part I: Inventing Neurosomatic Medicine: Rewards and Satisfactions versus Problems and Pitfalls * Chapter 1. The Education of a Neurosomaticist * Chapter 2. The Office Practice of Neurosomatic Medicine * Bankruptcy Despite a Three-Month Waiting List * Solving the Problems and Avoiding the Pitfalls * Taking Care of Business * Chapter 3. Lawyers and Litigation * Sample Pathophysiology of Posttraumatic Fibromyalgia * Mene, Mene, Tekel, Upharsin * Chapter 4. Treatment Case Examples * Instantaneous Neural Network Reconfiguration by Pharmacologic Modulation of Afferent Cranial Nerve Input * The Pathophysiology of CFS and Related Neurosomatic Disorders * Thyroid Function in Neurosomatic Disorders: Stimulation of Trigeminal Nerve Activity with Thyrotropin-Releasing Hormone (TRH) * Chapter 5. Case Reports * My So-Called Illness: Is It Real or All in My Head? * One-Second Epiphanies * My Most Unusual Case * Bug-of-the-Month Club * Chapter 6. Married to a Doctor Who Is Married to His Practice * Part II: Society for Neuroscience Conference Proceedings * Chapter 7. This Is . . . Los Angeles * Chapter 8. Neurosomatic Pearls * Eldritch Lore About Neurosomatic Therapy * Chapter 9. Neurosomatic Neuroscience * Part III: Pathophysiology and Treatment * Chapter 10. Treatment of Neurosomatic Disorders * Abecarnil and Acamprosate * Stimulants * The Corticostriatal-Thalamocortical (CSTC) Circuit in Reverse * Corticotropin-Releasing Hormone (CRH) and Hypocortisolism * Agmatine * Cholinesterase Inhibitors * Ascorbate (Vitamin C) * Amantadine * Adenosine * Baclofen * Gamma-Aminobutyric Acid (GABA) * Adenosine Triphosphate (ATP) * Lorazepam Nasal Spray * Antibiotics * Endothelin (ET) * Respiratory Rhythm Regulation in Fibromyalgia Syndrome * pH and Panic Disorder * Buspirone/BuSpar * Thalamic Reticular Nucleus * The Attentional Network * Clonidine * Catecholamines * Norepinephrine, Dopamine, Salience, and Attention * Dopamine and Reward * Effexor (Venlafaxine) * Synaptic Plasticity and Long-Term Potentiation in Neurosomatic Disorders * The Postreceptor Phosphorylation Cascade * The Treatment of Attentional Disorders * Instantaneous Neural Network Reconfiguration * Other Aspects of Synaptic Plasticity * Hormonal Modulation in Neurosomatic Medicine * Modulating the N-Methyl-D-Aspartate (NMDA) Receptor * Atypical Messengers * Synaptic Fatigue * Glutamate Receptors, Subunits, and Synaptic Scaling * Neurotrophic Factors * Metabotropic Glutamate Receptors * Conclusion * Chapter 11. Modulating Glutamatergic Neurotransmission * Ketamine * Pharmacologic Modulation of Sensory Integration via the Trigeminal Nerve * Electroconvulsive Therapy (ECT) * Kinases and Phosphatases * The Nicotinic Cholinergic Receptor * Long-Term Potentiation and Depression * Mitogen-Activated Protein Kinases (MAPKs) * Gabapentin * Zolpidem * Lamotrigine * Pentazocine (Talwin) * Oxytocin * Opioids * Oxytocin, Hypothalamic Function, and Circadian Rhythms * Other Effects of Oxytocin * Modafinil (Provigil) * Ventrolateral Preoptic Nucleus (VLPO) * Lidocaine * Gonadotropin-Releasing Hormone (GnRH) and Dysregulation of Circadian Rhythms * Pyrrolidines * Fatigue * Sleep * Conclusion * Conclusion. Closing the Circuit: The Role of the Nucleus Accumbens in Neurosomatic Disorders * Appendix * Diagnostic Criteria from the DSM-IV-TR * Treatment Algorithm * Medication List: Present and Near-Future Treatment Options for Neurosomatic Disorders * CFS Symptom Checklist * References * Index
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